BOČKOVÁ, Martina, Jan CHLÁDEK, Pavel JURÁK, Josef HALÁMEK, Klára ŠTILLOVÁ, Marek BALÁŽ, Jan CHRASTINA and Ivan REKTOR. Complex Motor-Cognitive Factors Processed in the Anterior Nucleus of the Thalamus: An Intracerebral Recording Study. BRAIN TOPOGRAPHY. DORDRECHT: SPRINGER, 2015, vol. 28, No 2, p. 269-278. ISSN 0896-0267. Available from: https://dx.doi.org/10.1007/s10548-014-0373-7.
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Basic information
Original name Complex Motor-Cognitive Factors Processed in the Anterior Nucleus of the Thalamus: An Intracerebral Recording Study
Authors BOČKOVÁ, Martina (203 Czech Republic, belonging to the institution), Jan CHLÁDEK (203 Czech Republic), Pavel JURÁK (203 Czech Republic), Josef HALÁMEK (203 Czech Republic), Klára ŠTILLOVÁ (703 Slovakia, belonging to the institution), Marek BALÁŽ (703 Slovakia, belonging to the institution), Jan CHRASTINA (203 Czech Republic, belonging to the institution) and Ivan REKTOR (203 Czech Republic, guarantor, belonging to the institution).
Edition BRAIN TOPOGRAPHY, DORDRECHT, SPRINGER, 2015, 0896-0267.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Netherlands
Confidentiality degree is not subject to a state or trade secret
WWW URL
Impact factor Impact factor: 3.727
RIV identification code RIV/00216224:14740/15:00080588
Organization unit Central European Institute of Technology
Doi http://dx.doi.org/10.1007/s10548-014-0373-7
UT WoS 000349853300008
Keywords in English Anterior nucleus of the thalamus; Complex cognitive functions; Deep brain stimulation; ERD/S; ERP
Tags podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Olga Křížová, učo 56639. Changed: 14/4/2016 16:03.
Abstract
Cognitive adverse effects were reported after the deep brain stimulation (DBS) of the anterior nucleus of the thalamus (AN) in epilepsy. As the AN may have an influence on widespread neocortical networks, we hypothesized that the AN, in addition to its participation in memory processing, may also participate in cognitive activities linked with the frontal neocortical structures. The aim of this study was to investigate whether the AN might participate in complex motor–cognitive activities. Three pharmacoresistant epilepsy patients implanted with AN–DBS electrodes performed two tasks involving the writing of single letters: (1) copying letters from a monitor; and (2) writing of any letter other than that appearing on the monitor. The cognitive load of the second task was increased. The task-related oscillatory changes and evoked potentials were assessed. Local event-related alpha and beta desynchronization were more expressed during the second task while the lower gamma synchronization decreased. The local field event-related potentials were elicited by the two tasks without any specific differences. The AN participates in cognitive networks processing complex motor–cognitive tasks. Attention should be paid to executive functions in subjects undergoing AN–DBS.
Links
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
GAP103/11/0933, research and development projectName: Analýza vysokofrekvenčního EEG signálu z hlubokých mozkových elektrod
Investor: Czech Science Foundation
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