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@article{1204565,
author = {OrtizanddeandSolórzano, Carlos and MuñozandBarrutia, Arrate and Meijering, Erik and Kozubek, Michal},
article_location = {New York},
article_number = {1},
doi = {http://dx.doi.org/10.1109/MSP.2014.2358263},
keywords = {cell model; image segmentation; cell tracking; cell synthesis},
language = {eng},
issn = {1053-5888},
journal = {IEEE Signal Processing Magazine},
title = {Toward a Morphodynamic Model of the Cell},
volume = {32},
year = {2015}
}
TY - JOUR
ID - 1204565
AU - Ortiz-de-Solórzano, Carlos - Muñoz-Barrutia, Arrate - Meijering, Erik - Kozubek, Michal
PY - 2015
TI - Toward a Morphodynamic Model of the Cell
JF - IEEE Signal Processing Magazine
VL - 32
IS - 1
SP - 20-29
EP - 20-29
PB - IEEE
SN - 10535888
KW - cell model
KW - image segmentation
KW - cell tracking
KW - cell synthesis
N2 - From a systems biology perspective, the cell is the principal element of information integration. Therefore, understanding the cell in its spatio-temporal context is the key to unraveling many of the still unknown mechanisms of life and disease. The purpose of this manuscript is to review image-processing aspects relevant to the quantification of cell morphology and dynamics. We cover both acquisition (hardware) and analysis (software) related issues, in a multi-scale fashion, from the detection of cellular components to the description of the entire cell in relation to its extracellular environment. Then, we describe ongoing efforts to integrate all this vast and diverse information along with data about the biomechanics of the cell, to create a credible model of cell morphology and behavior.
ER -
ORTIZ-DE-SOLÓRZANO, Carlos, Arrate MUÑOZ-BARRUTIA, Erik MEIJERING and Michal KOZUBEK. Toward a Morphodynamic Model of the Cell. \textit{IEEE Signal Processing Magazine}. New York: IEEE, 2015, vol.~32, No~1, p.~20-29. ISSN~1053-5888. Available from: https://dx.doi.org/10.1109/MSP.2014.2358263.
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