HRTYAN, Mónika, Eva ŠLIKOVÁ, Jan HEJÁTKO and Kamil RŮŽIČKA. The role of alternative splicing in auxin and cytokinin pathways. In 9th Tri-National Arabidopsis Meeting (TNAM) 2014. 2014.
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Basic information
Original name The role of alternative splicing in auxin and cytokinin pathways
Authors HRTYAN, Mónika (348 Hungary, guarantor, belonging to the institution), Eva ŠLIKOVÁ (703 Slovakia, belonging to the institution), Jan HEJÁTKO (203 Czech Republic, belonging to the institution) and Kamil RŮŽIČKA (203 Czech Republic, belonging to the institution).
Edition 9th Tri-National Arabidopsis Meeting (TNAM) 2014, 2014.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 10600 1.6 Biological sciences
Country of publisher Germany
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14310/14:00077162
Organization unit Faculty of Science
Keywords in English alternative splicing; PIN; AHP6; cell plate
Changed by Changed by: Olga Křížová, učo 56639. Changed: 13/4/2015 10:30.
Abstract
Alternative splicing is a tightly regulated process accompanying gene expression. It leads to multiple protein variants from a single primary transcipt. Transcriptome sequencing revealed that >60 % of Arabidopsis genes are alternatively spliced. This raises the question if all the identified isoforms have biologically functional relevance. Our aim is to answer this question for three members of auxin and cytokinin pathways: PIN4 (PINFORMED 4), PIN7 and AHP6 (ARABIDOPSIS HISTIDINE PHOSPHOTRANSFER PROTEIN 6), where all of them are known to be processed into more alternatively spliced mRNAs. PIN4 and PIN7 are processed into two isoforms called a and b, respectively, which differ in their subcellular localization. Also two isoforms of AHP6 have been described, AHP6b and AHP6a. We found that both of them are expressed as stable proteins and are actively transported into nuclei.
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EE2.3.20.0189, research and development projectName: Rozvoj výzkumné excelence v oblasti evoluční cytogenomiky, epigenetiky a buněčné signalizace
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