Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report

JIRSENSKÁ, Zlatava, Michaela MÁCHALOVÁ and Lukáš HOMOLA. Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report. In 32nd Annual Meeting of the European Society for Pediatric Infectious Diseases. 2014.

Basic information

Original name

Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report

Authors

JIRSENSKÁ, Zlatava (203 Czech Republic, guarantor, belonging to the institution), Michaela MÁCHALOVÁ (203 Czech Republic, belonging to the institution) and Lukáš HOMOLA (203 Czech Republic, belonging to the institution)

Edition

32nd Annual Meeting of the European Society for Pediatric Infectious Diseases, 2014

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Other information

Language

English

Type of outcome

Konferenční abstrakt

Field of Study

30300 3.3 Health sciences

Country of publisher

Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/14:00077208

Organization unit

Faculty of Medicine

Keywords in English

VACCINATION; LARYNGEAL PAPILLOMATOSIS

Tags

EL OK

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Abstract

V originále

We present a case report of one year old girl with recurrent laryngeal papillomatosis that was successfully treated by vaccination. The childs mother got condyloma acuminata during pregnancy. The disease was transmitted to the girl probably during delivery. At age of 5 months, the child started to present difficulties with breathing due to laryngeal papilomas. The disease required frequent papilectomies (almost every month) to maintain breathing. The papilomavirus type 11 was detected by PCR in the papiloma histology sample. At age of 18 months we started experimental vaccination with Gardasil* (it contains particles similar to HPV 6, 11, 16, 18). Intervals between necessary papilectomies were longer after the second dose of the vaccine. There was no need for further polypectomy after the third dose of the vaccine. At age of 30 months the child has no clinical and laryngoscope signs of laryngeal papillomatosis and the girl regained her voice. This case indicates possible new therapeutical approach to recurrent laryngeal papillomatosis.