JIRSENSKÁ, Zlatava, Michaela MÁCHALOVÁ and Lukáš HOMOLA. Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report. In 32nd Annual Meeting of the European Society for Pediatric Infectious Diseases. 2014.
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Basic information
Original name Impact of vaccination on the course of recurrent laryngeal papillomatosis - case report
Authors JIRSENSKÁ, Zlatava (203 Czech Republic, guarantor, belonging to the institution), Michaela MÁCHALOVÁ (203 Czech Republic, belonging to the institution) and Lukáš HOMOLA (203 Czech Republic, belonging to the institution).
Edition 32nd Annual Meeting of the European Society for Pediatric Infectious Diseases, 2014.
Other information
Original language English
Type of outcome Conference abstract
Field of Study 30300 3.3 Health sciences
Country of publisher Ireland
Confidentiality degree is not subject to a state or trade secret
RIV identification code RIV/00216224:14110/14:00077208
Organization unit Faculty of Medicine
Keywords in English VACCINATION; LARYNGEAL PAPILLOMATOSIS
Tags EL OK
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 27/11/2014 15:57.
Abstract
We present a case report of one year old girl with recurrent laryngeal papillomatosis that was successfully treated by vaccination. The childs mother got condyloma acuminata during pregnancy. The disease was transmitted to the girl probably during delivery. At age of 5 months, the child started to present difficulties with breathing due to laryngeal papilomas. The disease required frequent papilectomies (almost every month) to maintain breathing. The papilomavirus type 11 was detected by PCR in the papiloma histology sample. At age of 18 months we started experimental vaccination with Gardasil* (it contains particles similar to HPV 6, 11, 16, 18). Intervals between necessary papilectomies were longer after the second dose of the vaccine. There was no need for further polypectomy after the third dose of the vaccine. At age of 30 months the child has no clinical and laryngoscope signs of laryngeal papillomatosis and the girl regained her voice. This case indicates possible new therapeutical approach to recurrent laryngeal papillomatosis.
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