PAVLIŇÁK, David, Veronika ŠVACHOVÁ, Libor VOJTEK, Jana ZARZYCKÁ, Pavel HYRŠL, Milan ALBERTI and Lucy VOJTOVÁ. Plasma-chemical modifications of cellulose for biomedical applications. Open Chemistry. DE GRUYTER OPEN, 2014, vol. 13, No 1, p. 229-235. ISSN 2391-5420. Available from: https://dx.doi.org/10.1515/chem-2015-0030.
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Basic information
Original name Plasma-chemical modifications of cellulose for biomedical applications
Authors PAVLIŇÁK, David (203 Czech Republic, guarantor, belonging to the institution), Veronika ŠVACHOVÁ (203 Czech Republic), Libor VOJTEK (203 Czech Republic, belonging to the institution), Jana ZARZYCKÁ (203 Czech Republic, belonging to the institution), Pavel HYRŠL (203 Czech Republic, belonging to the institution), Milan ALBERTI (203 Czech Republic, belonging to the institution) and Lucy VOJTOVÁ (203 Czech Republic).
Edition Open Chemistry, DE GRUYTER OPEN, 2014, 2391-5420.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10305 Fluids and plasma physics
Country of publisher Poland
Confidentiality degree is not subject to a state or trade secret
WWW URL
RIV identification code RIV/00216224:14310/14:00077432
Organization unit Faculty of Science
Doi http://dx.doi.org/10.1515/chem-2015-0030
UT WoS 000355403100028
Keywords in English oxidized cellulose;oxycellulose;antibacterial;plasma-chemical treatment;plasma
Tags AKR
Tags International impact, Reviewed
Changed by Changed by: Mgr. David Pavliňák, Ph.D., učo 150650. Changed: 23/8/2016 11:15.
Abstract
A 6-carboxycellulose (in medicine known as “oxidized cellulose” or “oxycellulose”) is one of the cellulose derivatives popular in the field of surgery. Health products based on oxidized cellulose are great local hemostatics with unique bactericidal and fully bioabsorbable effects. Traditional process of native cellulose oxidation is described as a complex radical reaction in strong acidic liquid medium doped by toxic nitrous radicals (NO*). Our plasma-chemical reaction demonstrates a new synthesis method of oxidized cellulose with unique bactericidal effect. This plasma-chemical treatment is based on atmospheric plasma discharge in liquid medium leading to the oxidation of polysaccharide molecules resulting in oxycellulose. Final oxycellulose properties were evaluated by infrared spectroscopy and carboxyl content determination. The biological impact showed a strong germicidal effect.
Links
ED2.1.00/03.0086, research and development projectName: Regionální VaV centrum pro nízkonákladové plazmové a nanotechnologické povrchové úpravy
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