Cystatin of Eudiplozoon nipponicum - exploring the functional
molecules of Monogenea

D 2014

Cystatin of Eudiplozoon nipponicum - exploring the functional molecules of Monogenea

ILGOVÁ, Jana, Milan GELNAR and Martin KAŠNÝ

Basic information

Original name

Cystatin of Eudiplozoon nipponicum - exploring the functional molecules of Monogenea

Authors

ILGOVÁ, Jana (703 Slovakia, guarantor, belonging to the institution), Milan GELNAR (203 Czech Republic, belonging to the institution) and Martin KAŠNÝ (203 Czech Republic, belonging to the institution)

Edition

Brno, 3rd Workshop of European Centre of Ichthyoparasitology, p. 25-26, 2 pp. 2014

Publisher

MUNI PRESS

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10600 1.6 Biological sciences

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

printed version "print"

RIV identification code

RIV/00216224:14310/14:00074141

Organization unit

Faculty of Science

ISBN

978-80-210-7492-7

Keywords in English

Eudiplozoon nipponicum; functional molecules; cystatin

Změněno: 28/4/2015 09:07, Ing. Andrea Mikešková

Abstract

V originále

Cystatins, the inhibitors of cysteine peptidases, are expressed and released by many parasitic organisms. They are participating on regulation of biological processes, e.g., the modification of the host immune response. Our study is primarily focused on identification of genes of cystatins, characterization of molecular, biochemical and immunological properties of these molecules from four model species representing the four main groups of helmints, Monogenea are represented by Eudiplozoon nipponicum. Blood-feeding monogenean E. nipponicum parasitizing the gills of common carp (Cyprinus carpio) is widely distributed Euroasian ectoparasite from Diplozooidae family. The foregoing research has been oriented toward understanding the morphology and ecology of particular species from this taxonomic group. Currently only a little is known about the mechanisms of host-parasite interactions associated with the functional molecules produced by this parasites. Among these molecules appear also cystatins - inhibitors of cysteine peptidases. They were previously proven to play a substantial role in manipulation of the host immune response by various parasitic species and thus maximizing the parasite success. By revealing the function of cystatin of E. nipponicum we would like to complete the mosaic of present knowledge concerning the molecules from diplozoid parasites, which play a role in the host-parasite interaction and discuss the function of cystatins in the context of other multicellular parasitic organisms with different biological strategies.

Links

GBP505/12/G112, research and development project

Name: ECIP - Evropské centrum ichtyoparazitologie

Investor: Czech Science Foundation

Citovat

ILGOVÁ, Jana, Milan GELNAR and Martin KAŠNÝ. Cystatin of Eudiplozoon nipponicum - exploring the functional molecules of Monogenea. In 3rd Workshop of European Centre of Ichthyoparasitology. Brno: MUNI PRESS, 2014, p. 25-26. ISBN 978-80-210-7492-7.

@inproceedings{1210636,
   author = {Ilgová, Jana and Gelnar, Milan and Kašný, Martin},
   address = {Brno},
   booktitle = {3rd Workshop of European Centre of Ichthyoparasitology},
   keywords = {Eudiplozoon nipponicum; functional molecules; cystatin},
   howpublished = {tištěná verze "print"},
   language = {eng},
   location = {Brno},
   isbn = {978-80-210-7492-7},
   pages = {25-26},
   publisher = {MUNI PRESS},
   title = {Cystatin of Eudiplozoon nipponicum - exploring the functional molecules of Monogenea},
   year = {2014}
}

TY  - JOUR
ID  - 1210636
AU  - Ilgová, Jana - Gelnar, Milan - Kašný, Martin
PY  - 2014
TI  - Cystatin of Eudiplozoon nipponicum - exploring the functional molecules of Monogenea
PB  - MUNI PRESS
CY  - Brno
SN  - 9788021074927
KW  - Eudiplozoon nipponicum
KW  - functional molecules
KW  - cystatin
N2  - Cystatins, the inhibitors of cysteine peptidases, are expressed and released by many parasitic organisms. They are participating on regulation of biological processes, e.g., the modification of the host immune response. Our study is primarily focused on identification of genes of cystatins, characterization of molecular, biochemical and immunological properties of these molecules from four model species representing the four main groups of helmints, Monogenea are represented by Eudiplozoon nipponicum. Blood-feeding monogenean E. nipponicum parasitizing the gills of common carp (Cyprinus carpio) is widely distributed Euroasian ectoparasite from Diplozooidae family. The foregoing research has been oriented toward understanding the morphology and ecology of particular species from this taxonomic group. Currently only a little is known about the mechanisms of host-parasite interactions associated with the functional molecules produced by this parasites. Among these molecules appear also cystatins - inhibitors of cysteine peptidases. They were previously proven to play a substantial role in manipulation of the host immune response by various parasitic species and thus maximizing the parasite success. By revealing the function of cystatin of E. nipponicum we would like to complete the mosaic of present knowledge concerning the molecules from diplozoid parasites, which play a role in the host-parasite interaction and discuss the function of cystatins in the context of other multicellular parasitic organisms with different biological strategies.
ER  -

ILGOVÁ, Jana, Milan GELNAR and Martin KAŠNÝ. Cystatin of Eudiplozoon nipponicum - exploring the functional molecules of Monogenea. In \textit{3rd Workshop of European Centre of Ichthyoparasitology}. Brno: MUNI PRESS, 2014, p.~25-26. ISBN~978-80-210-7492-7.

Detailed Information on Publication Record