Heavy metals in hair samples: A pilot study of anaemic children
in Kazakhstan, Kyrgyzstan and Uzbekistan

J 2014

Heavy metals in hair samples: A pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan

DERFLEROVÁ BRÁZDOVÁ, Zuzana, Joceline POMERLEAU, Jindřich FIALA, Lenka VORLOVÁ, Dana MULLEROVÁ et. al.

Basic information

Original name

Heavy metals in hair samples: A pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan

Authors

DERFLEROVÁ BRÁZDOVÁ, Zuzana (203 Czech Republic, guarantor, belonging to the institution), Joceline POMERLEAU (826 United Kingdom of Great Britain and Northern Ireland), Jindřich FIALA (203 Czech Republic, belonging to the institution), Lenka VORLOVÁ (203 Czech Republic) and Dana MULLEROVÁ (203 Czech Republic)

Edition

Central European Journal of Public Health, Prague, Czech National Institute of Public Health, 2014, 1210-7778

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30304 Public and environmental health

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 0.533

RIV identification code

RIV/00216224:14110/14:00077586

Organization unit

Faculty of Medicine

UT WoS

000347140200011

Keywords in English

children; iron-deficiency anaemia; lead; cadmium; mercury

Abstract

V originále

Background: Heavy metals with their potential haematotoxic effect can contribute to the risks of anaemia in children in Central Asian Republics, where burden and exposure to these metals is still not sufficiently known and reported. Methods: Cross-sectional study was performed in Central Asian countries in hospitals in Kazakhstan, Kyrgyzstan, and Uzbekistan with the aim to investigate the potential contribution of heavy metals to anaemia in children. In each country, 20 children were recruited, all were hospitalised with diagnosed anaemia. A sample of hair was taken from each child to assess the hair concentration of lead, cadmium and mercury. Results: Relatively high levels of hair lead were observed, particularly in Kyrgyzstan. While lead and cadmium concentrations did not differ significantly among countries, mercury was lower in Kazakhstan than in Kyrgyzstan (p<0.05) and Uzbekistan (p<0.001). Hair lead and cadmium levels were significantly positively correlated (correlation coefficient=0.51, p<0.0001). Conclusion: The results of this study showed higher than expected levels of hair lead, cadmium and mercury in anaemic children. Because iron deficiency anaemia is a major public health problem in CAR, further investigation of the extent of exposure to heavy metal and of its contribution in iron deficiency anaemia in the region would be recommended.

Citovat

DERFLEROVÁ BRÁZDOVÁ, Zuzana, Joceline POMERLEAU, Jindřich FIALA, Lenka VORLOVÁ and Dana MULLEROVÁ. Heavy metals in hair samples: A pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan. Central European Journal of Public Health. Prague: Czech National Institute of Public Health, 2014, vol. 22, No 4, p. 273-276. ISSN 1210-7778.

@article{1211486,
   author = {Derflerová Brázdová, Zuzana and Pomerleau, Joceline and Fiala, Jindřich and Vorlová, Lenka and Mullerová, Dana},
   article_location = {Prague},
   article_number = {4},
   keywords = {children; iron-deficiency anaemia; lead; cadmium; mercury},
   language = {eng},
   issn = {1210-7778},
   journal = {Central European Journal of Public Health},
   title = {Heavy metals in hair samples: A pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan},
   volume = {22},
   year = {2014}
}

TY  - JOUR
ID  - 1211486
AU  - Derflerová Brázdová, Zuzana - Pomerleau, Joceline - Fiala, Jindřich - Vorlová, Lenka - Mullerová, Dana
PY  - 2014
TI  - Heavy metals in hair samples: A pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan
JF  - Central European Journal of Public Health
VL  - 22
IS  - 4
SP  - 273-276
EP  - 273-276
PB  - Czech National Institute of Public Health
SN  - 12107778
KW  - children
KW  - iron-deficiency anaemia
KW  - lead
KW  - cadmium
KW  - mercury
N2  - Background: Heavy metals with their potential haematotoxic effect can contribute to the risks of anaemia in children in Central Asian Republics, where burden and exposure to these metals is still not sufficiently known and reported. Methods: Cross-sectional study was performed in Central Asian countries in hospitals in Kazakhstan, Kyrgyzstan, and Uzbekistan with the aim to investigate the potential contribution of heavy metals to anaemia in children. In each country, 20 children were recruited, all were hospitalised with diagnosed anaemia. A sample of hair was taken from each child to assess the hair concentration of lead, cadmium and mercury. Results: Relatively high levels of hair lead were observed, particularly in Kyrgyzstan. While lead and cadmium concentrations did not differ significantly among countries, mercury was lower in Kazakhstan than in Kyrgyzstan (p<0.05) and Uzbekistan (p<0.001). Hair lead and cadmium levels were significantly positively correlated (correlation coefficient=0.51, p<0.0001). Conclusion: The results of this study showed higher than expected levels of hair lead, cadmium and mercury in anaemic children. Because iron deficiency anaemia is a major public health problem in CAR, further investigation of the extent of exposure to heavy metal and of its contribution in iron deficiency anaemia in the region would be recommended.
ER  -

DERFLEROVÁ BRÁZDOVÁ, Zuzana, Joceline POMERLEAU, Jindřich FIALA, Lenka VORLOVÁ and Dana MULLEROVÁ. Heavy metals in hair samples: A pilot study of anaemic children in Kazakhstan, Kyrgyzstan and Uzbekistan. \textit{Central European Journal of Public Health}. Prague: Czech National Institute of Public Health, 2014, vol.~22, No~4, p.~273-276. ISSN~1210-7778.

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