Early Outcomes of Alcohol Septal Ablation for Hypertrophic
Obstructive Cardiomyopathy: A European Multicenter and
Multinational Study

J 2014

Early Outcomes of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A European Multicenter and Multinational Study

VESELKA, Josef; Thorsten LAWRENZ; Christoph STELLBRINK; David ZEMANEK; Marian BRANNY et. al.

Základní údaje

Originální název

Early Outcomes of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A European Multicenter and Multinational Study

Autoři

VESELKA, Josef (203 Česká republika); Thorsten LAWRENZ (276 Německo); Christoph STELLBRINK (276 Německo); David ZEMANEK (203 Česká republika); Marian BRANNY (203 Česká republika); Jaroslav JANUSKA (203 Česká republika); Jan SITAR (203 Česká republika); Pawel DIMITROW (616 Polsko); Jan KREJČÍ (203 Česká republika, garant, domácí); Maciej DABROWSKI (616 Polsko); Stanislav MIZERA (703 Slovensko); Thomas BARTEL (40 Rakousko) a Horst KUHN (276 Německo)

Vydání

Catheterization and Cardiovascular Interventions, Hoboken, Wiley-Blackwell, 2014, 1522-1946

Další údaje

Jazyk

angličtina

Typ výsledku

Článek v odborném periodiku

Obor

30201 Cardiac and Cardiovascular systems

Stát vydavatele

Spojené státy

Utajení

není předmětem státního či obchodního tajemství

Impakt faktor

Impact factor: 2.107

Kód RIV

RIV/00216224:14110/14:00077664

Organizační jednotka

Lékařská fakulta

DOI

https://doi.org/10.1002/ccd.25236

UT WoS

000337970100021

EID Scopus

2-s2.0-84903535624

Klíčová slova anglicky

hypertrophic cardiomyopathy; alcohol septal ablation; cardiomyopathy

Štítky

EL OK

Příznaky

Mezinárodní význam, Recenzováno

Změněno: 5. 12. 2014 14:24, Soňa Böhmová

Anotace

V originále

Background: This study was designed to evaluate the outcomes of alcohol septal ablation (ASA) under multicenter and multinational conditions. Methods: Data for 459 patients (age 57 +/- 13 years) from nine European centers were prospectively collected and retrospectively analyzed. Results: ASA led to a significant reduction in outflow gradient (PG) and dyspnea [median of PG from 88 (58-123) mm Hg to 21 (11-41) mm Hg; median of NYHA class from 3 (2-3) to 1 (1-2); P < 0.01]. The incidence of 3-month major adverse events (death, electrical cardioversion for tachyarrhythmias, resuscitation) and mortality was 2.8% and 0.7%, respectively. Permanent pacemakers for post-ASA complete heart block were implanted in 43 patients (9%). Multivariate analysis identified higher amount of alcohol (however, in generally low-dose procedures), higher baseline left ventricular ejection fraction and higher age as independent predictors of PG decrease >= 50%. Conclusions: The results of the first European multicenter and multinational study demonstrate that real-world early outcomes of ASA patients are better than was reported in observations from the first decade after ASA introduction.

Citovat

VESELKA, Josef; Thorsten LAWRENZ; Christoph STELLBRINK; David ZEMANEK; Marian BRANNY; Jaroslav JANUSKA; Jan SITAR; Pawel DIMITROW; Jan KREJČÍ; Maciej DABROWSKI; Stanislav MIZERA; Thomas BARTEL a Horst KUHN. Early Outcomes of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A European Multicenter and Multinational Study. Catheterization and Cardiovascular Interventions. Hoboken: Wiley-Blackwell, 2014, roč. 84, č. 1, s. 101-107. ISSN 1522-1946. Dostupné z: https://doi.org/10.1002/ccd.25236.

@article{1211826,
   author = {Veselka, Josef and Lawrenz, Thorsten and Stellbrink, Christoph and Zemanek, David and Branny, Marian and Januska, Jaroslav and Sitar, Jan and Dimitrow, Pawel and Krejčí, Jan and Dabrowski, Maciej and Mizera, Stanislav and Bartel, Thomas and Kuhn, Horst},
   article_location = {Hoboken},
   article_number = {1},
   doi = {https://doi.org/10.1002/ccd.25236},
   keywords = {hypertrophic cardiomyopathy; alcohol septal ablation; cardiomyopathy},
   language = {eng},
   issn = {1522-1946},
   journal = {Catheterization and Cardiovascular Interventions},
   title = {Early Outcomes of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A European Multicenter and Multinational Study},
   volume = {84},
   year = {2014}
}

TY  - JOUR
ID  - 1211826
AU  - Veselka, Josef - Lawrenz, Thorsten - Stellbrink, Christoph - Zemanek, David - Branny, Marian - Januska, Jaroslav - Sitar, Jan - Dimitrow, Pawel - Krejčí, Jan - Dabrowski, Maciej - Mizera, Stanislav - Bartel, Thomas - Kuhn, Horst
PY  - 2014
TI  - Early Outcomes of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A European Multicenter and Multinational Study
JF  - Catheterization and Cardiovascular Interventions
VL  - 84
IS  - 1
SP  - 101-107
EP  - 101-107
PB  - Wiley-Blackwell
SN  - 15221946
KW  - hypertrophic cardiomyopathy
KW  - alcohol septal ablation
KW  - cardiomyopathy
N2  - Background: This study was designed to evaluate the outcomes of alcohol septal ablation (ASA) under multicenter and multinational conditions. Methods: Data for 459 patients (age 57 +/- 13 years) from nine European centers were prospectively collected and retrospectively analyzed. Results: ASA led to a significant reduction in outflow gradient (PG) and dyspnea [median of PG from 88 (58-123) mm Hg to 21 (11-41) mm Hg; median of NYHA class from 3 (2-3) to 1 (1-2); P < 0.01]. The incidence of 3-month major adverse events (death, electrical cardioversion for tachyarrhythmias, resuscitation) and mortality was 2.8% and 0.7%, respectively. Permanent pacemakers for post-ASA complete heart block were implanted in 43 patients (9%). Multivariate analysis identified higher amount of alcohol (however, in generally low-dose procedures), higher baseline left ventricular ejection fraction and higher age as independent predictors of PG decrease >= 50%. Conclusions: The results of the first European multicenter and multinational study demonstrate that real-world early outcomes of ASA patients are better than was reported in observations from the first decade after ASA introduction.
ER  -

VESELKA, Josef; Thorsten LAWRENZ; Christoph STELLBRINK; David ZEMANEK; Marian BRANNY; Jaroslav JANUSKA; Jan SITAR; Pawel DIMITROW; Jan KREJČÍ; Maciej DABROWSKI; Stanislav MIZERA; Thomas BARTEL a Horst KUHN. Early Outcomes of Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy: A European Multicenter and Multinational Study. \textit{Catheterization and Cardiovascular Interventions}. Hoboken: Wiley-Blackwell, 2014, roč.~84, č.~1, s.~101-107. ISSN~1522-1946. Dostupné z: https://doi.org/10.1002/ccd.25236.

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