J 2014

Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study

LUDKA, Ondřej, Radka ŠTĚPÁNOVÁ, Martina VYSKOCILOVA, Lujza ZIKMUND GALKOVÁ, Monika MIKOLÁŠKOVÁ et. al.

Basic information

Original name

Sleep apnea prevalence in acute myocardial infarction - The Sleep Apnea in Post-acute Myocardial Infarction Patients (SAPAMI) Study

Authors

LUDKA, Ondřej (203 Czech Republic, guarantor, belonging to the institution), Radka ŠTĚPÁNOVÁ (203 Czech Republic, belonging to the institution), Martina VYSKOCILOVA (203 Czech Republic), Lujza ZIKMUND GALKOVÁ (703 Slovakia, belonging to the institution), Monika MIKOLÁŠKOVÁ (703 Slovakia, belonging to the institution), Milos BELEHRAD (203 Czech Republic), Jana KOSTALOVA (203 Czech Republic), Zuzana MIHALOVÁ (703 Slovakia), Adéla DROZDOVÁ (203 Czech Republic, belonging to the institution), Jiří HLÁSENSKÝ (203 Czech Republic, belonging to the institution), Michal GACÍK (703 Slovakia, belonging to the institution), Lucie PUDILOVÁ (203 Czech Republic, belonging to the institution), Tereza MIKUŠOVÁ (203 Czech Republic), Blanka FISCHEROVÁ (203 Czech Republic), Fatima SERT-KUNIYOSHI (840 United States of America), Virend K. SOMERS (840 United States of America), Jindřich ŠPINAR (203 Czech Republic, belonging to the institution) and Tomáš KÁRA (203 Czech Republic)

Edition

International Journal of Cardiology, Clare, Elsevier Ireland Ltd. 2014, 0167-5273

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

Ireland

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.036

RIV identification code

RIV/00216224:14110/14:00077695

Organization unit

Faculty of Medicine

DOI

UT WoS

000341040900015

Keywords in English

Sleep apnea; Acute myocardial infarction; Prevalence; Day-night variation

Tags

Tags

International impact, Reviewed
Změněno: 9/12/2014 11:25, Soňa Böhmová

Abstract

V originále

Background: While sleep apnea (SA) might be a modifiable cardiovascular risk factor, recent data suggest that SA is severely underdiagnosed in patients after acute myocardial infarction (MI). There is limited evidence about day-night variation of onset of MI on dependence of having SA. We therefore investigated the prevalence of SA and examined the day-night variation of onset of MI in acute MI patients. Methods: We prospectively studied 782 consecutive patients admitted to the hospital with the diagnosis of acute MI. All subjects underwent sleep evaluations using a portable device after at least 48 h post-admission. Using the apnea-hypopnea index (AHI), groups were defined as patients without SA (<5 events/h), mild SA (5-15 events/h), moderate SA (15-30 events/h), and severe SA (>= 30 events/h). Results: Almost all patients (98%) underwent urgent coronary angiography and 91% of patients underwent primary PCI. Using a threshold of AHI >= 5 events/h, SA was present in 65.7% of patients after acute MI. Mild SA was present in 32.6%, moderate in 20.4% and severe in 12.7%. The day-night variation in the onset of MI in all groups of SA patients was similar to that observed in non-SA patients. From 6 AM to 12 PM, the frequency of MI was higher in both SA and non-SA patients, as compared to the interval from 12 AM to 6 AM (all p < 0.05). Conclusion: There is a high prevalence of SA in patients presenting with acute MI. Peak time of MI onset in SA patients was between 6 AM and noon, similar to that in the general population. Whether diagnosis and treatment of SA after MI will significantly improve outcomes in these patients remains to be determined.