ADAMOVÁ, Blanka, Roman KOPÁČIK, Stanislav VOHÁŇKA, Ladislav DUŠEK and Josef BEDNAŘÍK. Is Electrophysiology Useful in the Differential Diagnostics of Lumbar Spinal Stenosis and Diabetic Polyneuropathy? Česká a Slovenská neurologie a neurochirurgie. Praha: Česká lékařská společnost J.E. Purkyně, 2014, vol. 77, No 6, p. 684-690. ISSN 1210-7859.
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Basic information
Original name Is Electrophysiology Useful in the Differential Diagnostics of Lumbar Spinal Stenosis and Diabetic Polyneuropathy?
Name in Czech Je elektrofyziologické vyšetření přínosné v diferenciální diagnostice lumbální spinální stenózy a diabetické polyneuropatie?
Authors ADAMOVÁ, Blanka (203 Czech Republic, guarantor, belonging to the institution), Roman KOPÁČIK (703 Slovakia, belonging to the institution), Stanislav VOHÁŇKA (203 Czech Republic, belonging to the institution), Ladislav DUŠEK (203 Czech Republic, belonging to the institution) and Josef BEDNAŘÍK (203 Czech Republic, belonging to the institution).
Edition Česká a Slovenská neurologie a neurochirurgie, Praha, Česká lékařská společnost J.E. Purkyně, 2014, 1210-7859.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 0.165
RIV identification code RIV/00216224:14110/14:00077839
Organization unit Faculty of Medicine
UT WoS 000346229200003
Keywords (in Czech) lumbální spinální stenóza; diabetická polyneuropatie; elektrofyziologické vyšetření; elektromyografie
Keywords in English lumbar spinal stenosis; diabetic polyneuropathy; electrophysiological examination; electromyography
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 13/3/2015 14:11.
Abstract
Aim: To evaluate validity of electrophysiological examination in the differential diagnostics of lumbar spinal stenosis (LS) and diabetic polyneuropathy (DPN). Methods: Electrophysiological parameters were examined in 68 patients with clinically symptomatic LS, in 28 patients with DPN, and in a group of 32 healthy volunteers. Results: Electrophysiological parameters evaluated from the upper extremities (F-wave latency of the ulnar nerve and radial SNAP amplitude), all the latencies measured in the lower extremities (tibial F-wave, soleus H-reflex and spinal latency of MEP), and the sural SNAP amplitude contributed significantly to distinguishing the LS from DPN patients. ROC analysis, however, disclosed only two electrophysiological parameters as effective in independent discrimination between the LS and DPN patient groups: ulnar F-wave latency (cut-off point at 24.2 ms, sensitivity 82.7% and specificity 63.9%); and radial SNAP amplitude (cut-off point at 10.5 µV, sensitivity 75.5%, specificity 58.2%). Multivariate discrimination provided a canonical score with the most powerful predictive value of all. Conclusions: Electrophysiological examination evaluated from the upper extremities proved very useful in the differential diagnostics of LS and DPN, but the most powerful predictive value was obtained by using a canonical score involving several electrophysiological parameters.
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