MATOUŠEK, Aleš, Martina KUKLETOVÁ and Jaroslav CIHLÁŘ. Influence of nanograin size of ZrO2 and Al2O3 ceramics on biological response of cells. In Key Engineering Materials. STAFA-ZURICH: TRANS TECH PUBLICATIONS LTD, 2014, p. 132-137. ISSN 1013-9826. Available from: https://dx.doi.org/10.4028/www.scientific.net/KEM.587.132.
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Basic information
Original name Influence of nanograin size of ZrO2 and Al2O3 ceramics on biological response of cells
Name in Czech Vliv velikosti nanozrna keramiky ZrO2 a AL2O3 na biologickou aktivitu buněk
Authors MATOUŠEK, Aleš (203 Czech Republic, guarantor), Martina KUKLETOVÁ (203 Czech Republic, belonging to the institution) and Jaroslav CIHLÁŘ (203 Czech Republic).
Edition STAFA-ZURICH, Key Engineering Materials, p. 132-137, 6 pp. 2014.
Publisher TRANS TECH PUBLICATIONS LTD
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 20600 2.6 Medical engineering
Country of publisher Switzerland
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
Impact factor Impact factor: 0.224 in 2005
RIV identification code RIV/00216224:14110/14:00077996
Organization unit Faculty of Medicine
ISSN 1013-9826
Doi http://dx.doi.org/10.4028/www.scientific.net/KEM.587.132
UT WoS 000336185000022
Keywords (in Czech) Aluminium; zirconium; bioactivita; adhese buněk;buněčná proliferace; osteoblast
Keywords in English Alumina; zirconia; bioactivity; cell adhesion; cell proliferation; osteoblast cell; surface roughness
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 24/3/2015 16:43.
Abstract
The influence of the grain size of alumina and zirconia ceramics on the spreading and adhesion of MG63 cell lines was investigated. Single-component ceramics and layered composite ceramics were prepared by electrophoretic deposition, uniaxial pressing and sintering. The grain size of zirconia was 100 urn to 2.7 mu m and that of alumina was 0.5 mu m to 1.5 mu m. Subsequently, sample surfaces were polished and thermally etched. Biological tests of adhesion (0.5 to 8 h) were used to evaluate the influence of grain size on biological response. The highest cell spreading and adhesion was obtained for ZrO2 ceramics with an average grain size of 100 and 120 nm. The cell selection was observed on layered ZrO2/Al2O3 composites. The cells predominantly adhered to ZrO2 layers. The results showed a positive influence of nanostructured ceramic surfaces on biological behaviour of MG63 cells.
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