Detailed Information on Publication Record
2014
Fragmentation pattern of shape-persistent macrocycles: a mass spectrometric study
AMATO, Filippo, Bhimrao Vaijnath PHULWALE, Ctibor MAZAL and Josef HAVELBasic information
Original name
Fragmentation pattern of shape-persistent macrocycles: a mass spectrometric study
Authors
AMATO, Filippo (380 Italy, belonging to the institution), Bhimrao Vaijnath PHULWALE (356 India, belonging to the institution), Ctibor MAZAL (203 Czech Republic, belonging to the institution) and Josef HAVEL (203 Czech Republic, guarantor, belonging to the institution)
Edition
ESAS 2014, 2014
Other information
Language
English
Type of outcome
Prezentace na konferencích
Field of Study
10406 Analytical chemistry
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/14:00074303
Organization unit
Faculty of Science
Keywords (in Czech)
mass spectrometry; shape-persistent macrocycles; MALDI-TOF
Keywords in English
mass spectrometry; shape-persistent macrocycles; MALDI-TOF
Tags
International impact, Reviewed
Změněno: 9/9/2015 16:03, doc. RNDr. Ctibor Mazal, CSc.
Abstract
V originále
Shape-persistent macrocycles (SPMs) are organic molecules characterized by a rigid non-collapsing ring with a cavity of fixed size. The ring can be either fully or partially conjugated. The properties of such macrocycles can be altered by derivatization with suitable substituents on the ring structure [1]. SPMs have wide application as building blocks for the “bottom-up” design and development of highly organised supramolecular architectures [2], nano-materials, nano-sized molecular devices, receptors, selective catalysts, chelators, discotic liquid crystals, metal organic frameworks, etc. Systematic mass spectrometric study of the fragmentation pattern of SPMs induced by pulsed laser and/or by collisions in quadrupole ion trap (QIT) has not been carried out up to now. The aim of this work is to: i) study the laser- and collision-induced fragmentation pathways of a series of shape-persistent macrocycles, ii) search for self-assembled supramolecular aggregates and iii) study the effect of fullerene as matrix by Matrix-Assisted Laser Desorption Ionisation Quadrupole-Ion-Trap Time-of-Flight Mass Spectrometry (MALDI-QIT-TOF-MS). Collision-induced fragmentation patterns of fifteen SPMs were studied by MALDI-QIT-TOF-MS and the stoichiometry of detected fragments was determined by modelling of the isotopic pattern. It was found that the use of fullerene as MALDI matrix enhances the laser-induced fragmentation during mass spectrometric analysis. The study of the fragmentation patterns of SPMs is useful for understanding their gas-phase behaviour after laser-induced excitation.
Links
| ED2.1.00/03.0086, research and development project |
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| GA13-05082S, research and development project |
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