J 2014

Czech multicenter research database of severe COPD

NOVOTNA, Barbora, V. KOBLIZEK, J. ZATLOUKAL, Marek PLUTINSKÝ, Karel HEJDUK et. al.

Basic information

Original name

Czech multicenter research database of severe COPD

Authors

NOVOTNA, Barbora (203 Czech Republic), V. KOBLIZEK (203 Czech Republic), J. ZATLOUKAL (203 Czech Republic), Marek PLUTINSKÝ (703 Slovakia, belonging to the institution), Karel HEJDUK (203 Czech Republic, belonging to the institution), Zuzana ZBOŽÍNKOVÁ (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, guarantor, belonging to the institution), O. SOBOTIK (203 Czech Republic), T. DVORAK (203 Czech Republic) and P. SAFRANEK (203 Czech Republic)

Edition

International Journal of chronic obstructive pulmonary disease, Albany, Dove Medical Press Ltd. 2014, 1178-2005

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30203 Respiratory systems

Country of publisher

New Zealand

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 3.141

RIV identification code

RIV/00216224:14110/14:00078311

Organization unit

Faculty of Medicine

UT WoS

000344926200001

Keywords in English

phenotypes; comorbidities; exacerbations; all-cause mortality; prospective study

Tags

Tags

International impact, Reviewed
Změněno: 24/4/2015 14:01, Ing. Mgr. Věra Pospíšilíková

Abstract

V originále

Purpose: Chronic obstructive pulmonary disease (COPD) has been recognized as a heterogeneous, multiple organ system-affecting disorder. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) places emphasis on symptom and exacerbation management. The aim of this study is examine the course of COPD and its impact on morbidity and all-cause mortality of patients, with respect to individual phenotypes and GOLD categories. This study will also evaluate COPD real-life patient care in the Czech Republic. Patients and methods: The Czech Multicentre Research Database of COPD is projected to last for 5 years, with the aim of enrolling 1,000 patients. This is a multicenter, observational, and prospective study of patients with severe COPD (post-bronchodilator forced expiratory volume in 1 second <= 60%). Every consecutive patient, who fulfils the inclusion criteria, is asked to participate in the study. Patient recruitment is done on the basis of signed informed consent. The study was approved by the Multicentre Ethical Committee in Brno, Czech Republic. Results: The objective of this paper was to outline the methodology of this study. Conclusion: The establishment of the database is a useful step in improving care for COPD subjects. Additionally, it will serve as a source of data elucidating the natural course of COPD, comorbidities, and overall impact on the patients. Moreover, it will provide information on the diverse course of the COPD syndrome in the Czech Republic.

Links

15/14/NAP, interní kód MU
Name: Sledování výskytu deficitu alfa 1 antitrypsinu u pacientů s těžkou formou CHOPN
Investor: Ministry of Health of the CR