NOVOTNA, Barbora, V. KOBLIZEK, J. ZATLOUKAL, Marek PLUTINSKÝ, Karel HEJDUK, Zuzana ZBOŽÍNKOVÁ, Jiří JARKOVSKÝ, O. SOBOTIK, T. DVORAK and P. SAFRANEK. Czech multicenter research database of severe COPD. International Journal of chronic obstructive pulmonary disease. Albany: Dove Medical Press Ltd., 2014, vol. 2014, No 9, p. 1265-1274. ISSN 1178-2005. Available from: https://dx.doi.org/10.2147/COPD.S71828.
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Basic information
Original name Czech multicenter research database of severe COPD
Authors NOVOTNA, Barbora (203 Czech Republic), V. KOBLIZEK (203 Czech Republic), J. ZATLOUKAL (203 Czech Republic), Marek PLUTINSKÝ (703 Slovakia, belonging to the institution), Karel HEJDUK (203 Czech Republic, belonging to the institution), Zuzana ZBOŽÍNKOVÁ (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, guarantor, belonging to the institution), O. SOBOTIK (203 Czech Republic), T. DVORAK (203 Czech Republic) and P. SAFRANEK (203 Czech Republic).
Edition International Journal of chronic obstructive pulmonary disease, Albany, Dove Medical Press Ltd. 2014, 1178-2005.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30203 Respiratory systems
Country of publisher New Zealand
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 3.141
RIV identification code RIV/00216224:14110/14:00078311
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.2147/COPD.S71828
UT WoS 000344926200001
Keywords in English phenotypes; comorbidities; exacerbations; all-cause mortality; prospective study
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 24/4/2015 14:01.
Abstract
Purpose: Chronic obstructive pulmonary disease (COPD) has been recognized as a heterogeneous, multiple organ system-affecting disorder. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) places emphasis on symptom and exacerbation management. The aim of this study is examine the course of COPD and its impact on morbidity and all-cause mortality of patients, with respect to individual phenotypes and GOLD categories. This study will also evaluate COPD real-life patient care in the Czech Republic. Patients and methods: The Czech Multicentre Research Database of COPD is projected to last for 5 years, with the aim of enrolling 1,000 patients. This is a multicenter, observational, and prospective study of patients with severe COPD (post-bronchodilator forced expiratory volume in 1 second <= 60%). Every consecutive patient, who fulfils the inclusion criteria, is asked to participate in the study. Patient recruitment is done on the basis of signed informed consent. The study was approved by the Multicentre Ethical Committee in Brno, Czech Republic. Results: The objective of this paper was to outline the methodology of this study. Conclusion: The establishment of the database is a useful step in improving care for COPD subjects. Additionally, it will serve as a source of data elucidating the natural course of COPD, comorbidities, and overall impact on the patients. Moreover, it will provide information on the diverse course of the COPD syndrome in the Czech Republic.
Links
15/14/NAP, interní kód MUName: Sledování výskytu deficitu alfa 1 antitrypsinu u pacientů s těžkou formou CHOPN
Investor: Ministry of Health of the CR
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