J 2014

Improvement in Quality of Life After Catheter Ablation for Paroxysmal Versus Long-standing Persistent Atrial Fibrillation: A Prospective Study With 3-Year Follow-up

BULKOVÁ, Veronika, Martin FIALA, Štěpán HAVRÁNEK, Jan ŠIMEK, Libor ŠKŇOUŘIL et. al.

Basic information

Original name

Improvement in Quality of Life After Catheter Ablation for Paroxysmal Versus Long-standing Persistent Atrial Fibrillation: A Prospective Study With 3-Year Follow-up

Authors

BULKOVÁ, Veronika (203 Czech Republic), Martin FIALA (203 Czech Republic, belonging to the institution), Štěpán HAVRÁNEK (203 Czech Republic), Jan ŠIMEK (203 Czech Republic), Libor ŠKŇOUŘIL (203 Czech Republic), Jaroslav JANUŠKA (203 Czech Republic), Jindřich ŠPINAR (203 Czech Republic, guarantor, belonging to the institution) and Dan WICHTERLE (203 Czech Republic)

Edition

Journal of the American Heart Association, Hoboken, Wiley-Blackwell, 2014, 2047-9980

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30201 Cardiac and Cardiovascular systems

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.306

RIV identification code

RIV/00216224:14110/14:00078476

Organization unit

Faculty of Medicine

UT WoS

000341296600016

Keywords in English

atrial fibrillation; long-standing persistent; paroxysmal; quality of life

Tags

Tags

International impact, Reviewed
Změněno: 19/1/2015 11:53, Soňa Böhmová

Abstract

V originále

Background-Changes in quality of life (QoL) after catheter ablation for long-standing persistent atrial fibrillation (LSPAF) are not well described. We sought to compare QoL improvement after catheter ablation of paroxysmal atrial fibrillation (PAF) versus that after LSPAF. Methods and Results-A total of 261 PAF and 126 LSPAF ablation recipients were prospectively followed for arrhythmia recurrence, QoL, hospital stay, and sick leave. In PAF versus LSPAF groups, 1.3 +/- 0.6 versus 1.6 +/- 0.7 procedures were performed per patient (P<0.00001) during a 3-year follow-up. Good arrhythmia control was achieved in 86% versus 87% of patients (P=0.69) and in 69% versus 69% of patients not receiving antiarrhythmic drugs (P=0.99). The baseline QoL was better in the PAF than in the LSPAF group (European Quality of Life Group instrument self-report questionnaire visual analog scale: 66.4 +/- 14.2 versus 61.0 +/- 14.2, P=0.0005; European Quality of Life Group 3-level, 5-dimensional descriptive system: 71.4 +/- 9.2 versus 67.7 +/- 13.8, P=0.002). Postablation 3-year increase in QoL was significant in both groups (all P<0.00001) and significantly lower in PAF versus LSPAF patients (visual analog scale: +5.0 +/- 14.5 versus +10.2 +/- 12.8, P=0.001; descriptive system: +5.9 +/- 14.3 versus +9.3 +/- 13.9, P=0.03). In multivariate analysis, LSPAF, less advanced age, shorter history of AF and good arrhythmia control were consistently associated with postablation 3-year improvement in QoL. Days of hospital stay for cardiovascular reasons and days on sick leave per patient/year were significantly reduced in both groups. Conclusions-Patients with LSPAF had worse baseline QoL. The magnitude of QoL improvement after ablation of LSPAF was significantly greater compared with after ablation of PAF, particularly when good arrhythmia control was achieved without the use of antiarrhythmic drugs.