Different Clinical Utility of Oropharyngeal Bacterial Screening
prior to Percutaneous Endoscopic Gastrostomy in Oncological and
Neurological Patients

J 2014

Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients

KROUPA, Radek, Jana JURÁNKOVÁ, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš PAVLÍK et. al.

Basic information

Original name

Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients

Authors

KROUPA, Radek (203 Czech Republic, guarantor, belonging to the institution), Jana JURÁNKOVÁ (203 Czech Republic, belonging to the institution), Milan DASTYCH (203 Czech Republic, belonging to the institution), Michal ŠENKYŘÍK (203 Czech Republic), Tomáš PAVLÍK (203 Czech Republic, belonging to the institution), Jitka PROKEŠOVÁ (203 Czech Republic, belonging to the institution), Markéta JEČMENOVÁ (203 Czech Republic, belonging to the institution), Jiří DOLINA (203 Czech Republic, belonging to the institution) and Aleš HEP (203 Czech Republic, belonging to the institution)

Edition

BioMed Research International, New York, Hindawi Publishing Corporation, 2014, 2314-6133

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Biotechnology and bionics

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.579

RIV identification code

RIV/00216224:14110/14:00078532

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1155/2014/590891

UT WoS

000344286300001

Keywords in English

RESISTANT STAPHYLOCOCCUS-AUREUS; RANDOMIZED CONTROLLED-TRIAL; ANTIBIOTIC-PROPHYLAXIS; SITE INFECTION; RISK-FACTORS; GASTROINTESTINAL ENDOSCOPY; PERISTOMAL INFECTION; TUBE INSERTION; COMPLICATIONS; COLONIZATION

Abstract

V originále

Background. The aim of this study was to monitor oropharyngeal bacterial colonization in patients indicated for percutaneous endoscopic gastronomy (PEG). Methods. Oropharyngeal swabs were obtained from patients prior to PEG placement. A development of peristomal infection was evaluated. The analysis of oropharyngeal and peristomal site pathogens was done. Results. Consecutive 274 patients referred for PEG due to neurological disorder or cancer completed the study. Oropharyngeal colonization with pathogens was observed in 69%(190/274), dominantly in the neurologic subgroup of patients (P < 0.001). Peristomal infection occurred in 30 (10.9%) of patients and in 57% of them the correlation between oropharyngeal and peristomal agents was present. The presence of oropharyngeal pathogens was assessed as an important risk factor for the development of peristomal infection only in oncological patients (OR = 8.33, 95% CI: 1.66-41.76). Despite a high prevalence of pathogens in neurological patients, it did not influence the risk of peristomal infection with the exception for methicillin resistant Staphylococcus aureus (MRSA) carriers (OR 4.5, 95% CI: 1.08-18.76). Conclusion. During oropharyngeal microbial screening prior to the PEG insertion, the detection of pathogens may be a marker of the increased risk of peristomal infection in cancer patients only. In neurological patients the benefit of the screening is limited to the detection of MRSA carriers.

Citovat

KROUPA, Radek, Jana JURÁNKOVÁ, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš PAVLÍK, Jitka PROKEŠOVÁ, Markéta JEČMENOVÁ, Jiří DOLINA and Aleš HEP. Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients. BioMed Research International. New York: Hindawi Publishing Corporation, 2014, vol. 2014, "590891", p. 1-7. ISSN 2314-6133. Available from: https://dx.doi.org/10.1155/2014/590891.

@article{1217590,
   author = {Kroupa, Radek and Juránková, Jana and Dastych, Milan and Šenkyřík, Michal and Pavlík, Tomáš and Prokešová, Jitka and Ječmenová, Markéta and Dolina, Jiří and Hep, Aleš},
   article_location = {New York},
   article_number = {"590891"},
   doi = {http://dx.doi.org/10.1155/2014/590891},
   keywords = {RESISTANT STAPHYLOCOCCUS-AUREUS; RANDOMIZED CONTROLLED-TRIAL; ANTIBIOTIC-PROPHYLAXIS; SITE INFECTION; RISK-FACTORS; GASTROINTESTINAL ENDOSCOPY; PERISTOMAL INFECTION; TUBE INSERTION; COMPLICATIONS; COLONIZATION},
   language = {eng},
   issn = {2314-6133},
   journal = {BioMed Research International},
   title = {Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients},
   volume = {2014},
   year = {2014}
}

TY  - JOUR
ID  - 1217590
AU  - Kroupa, Radek - Juránková, Jana - Dastych, Milan - Šenkyřík, Michal - Pavlík, Tomáš - Prokešová, Jitka - Ječmenová, Markéta - Dolina, Jiří - Hep, Aleš
PY  - 2014
TI  - Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients
JF  - BioMed Research International
VL  - 2014
IS  - "590891"
SP  - 1-7
EP  - 1-7
PB  - Hindawi Publishing Corporation
SN  - 23146133
KW  - RESISTANT STAPHYLOCOCCUS-AUREUS
KW  - RANDOMIZED CONTROLLED-TRIAL
KW  - ANTIBIOTIC-PROPHYLAXIS
KW  - SITE INFECTION
KW  - RISK-FACTORS
KW  - GASTROINTESTINAL ENDOSCOPY
KW  - PERISTOMAL INFECTION
KW  - TUBE INSERTION
KW  - COMPLICATIONS
KW  - COLONIZATION
N2  - Background. The aim of this study was to monitor oropharyngeal bacterial colonization in patients indicated for percutaneous endoscopic gastronomy (PEG). Methods. Oropharyngeal swabs were obtained from patients prior to PEG placement. A development of peristomal infection was evaluated. The analysis of oropharyngeal and peristomal site pathogens was done. Results. Consecutive 274 patients referred for PEG due to neurological disorder or cancer completed the study. Oropharyngeal colonization with pathogens was observed in 69%(190/274), dominantly in the neurologic subgroup of patients (P < 0.001). Peristomal infection occurred in 30 (10.9%) of patients and in 57% of them the correlation between oropharyngeal and peristomal agents was present. The presence of oropharyngeal pathogens was assessed as an important risk factor for the development of peristomal infection only in oncological patients (OR = 8.33, 95% CI: 1.66-41.76). Despite a high prevalence of pathogens in neurological patients, it did not influence the risk of peristomal infection with the exception for methicillin resistant Staphylococcus aureus (MRSA) carriers (OR 4.5, 95% CI: 1.08-18.76). Conclusion. During oropharyngeal microbial screening prior to the PEG insertion, the detection of pathogens may be a marker of the increased risk of peristomal infection in cancer patients only. In neurological patients the benefit of the screening is limited to the detection of MRSA carriers.
ER  -

KROUPA, Radek, Jana JURÁNKOVÁ, Milan DASTYCH, Michal ŠENKYŘÍK, Tomáš PAVLÍK, Jitka PROKEŠOVÁ, Markéta JEČMENOVÁ, Jiří DOLINA and Aleš HEP. Different Clinical Utility of Oropharyngeal Bacterial Screening prior to Percutaneous Endoscopic Gastrostomy in Oncological and Neurological Patients. \textit{BioMed Research International}. New York: Hindawi Publishing Corporation, 2014, vol.~2014, ''590891'', p.~1-7. ISSN~2314-6133. Available from: https://dx.doi.org/10.1155/2014/590891.

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