ŠVANDOVÁ, Eva, Barbora VESELÁ, Jan KŘIVÁNEK, Aleš HAMPL and E. MATALOVÁ. Recent Approaches in Tooth Engineering Research. Folia biologica. Praha: 1. lékařská fakulta Univerzity Karlovy v Praze, 2014, vol. 60, Supplement 1, p. 21-29. ISSN 0015-5500.
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Basic information
Original name Recent Approaches in Tooth Engineering Research
Authors ŠVANDOVÁ, Eva (203 Czech Republic, guarantor, belonging to the institution), Barbora VESELÁ (203 Czech Republic, belonging to the institution), Jan KŘIVÁNEK (203 Czech Republic, belonging to the institution), Aleš HAMPL (203 Czech Republic, belonging to the institution) and E. MATALOVÁ (203 Czech Republic).
Edition Folia biologica, Praha, 1. lékařská fakulta Univerzity Karlovy v Praze, 2014, 0015-5500.
Other information
Original language English
Type of outcome Article in a journal
Field of Study Genetics and molecular biology
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.000
RIV identification code RIV/00216224:14110/14:00074354
Organization unit Faculty of Medicine
UT WoS 000343275800004
Keywords in English engineering; tooth; stem cells; culture techniques
Tags EL OK, podil
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 23/1/2015 15:29.
Abstract
Tooth absence and defects caused by various reasons are frequent events in humans. They are not life threatening but may bring about social consequences. Recent dentistry provides solutions in the form of prosthetics or dental implants; however, several complications and distinct limitations favour bioengineering of dental and periodontal structures. At least two types of cells (epithelial and mesenchymal) have to be recombined to produce a new functional tooth. Moreover, the tooth must be vascularized, innervated and properly anchored in the bone. To study these issues, different approaches have been established in both basic and applied research. In this review, recent strategies and techniques of tooth engineering are comprehensively summarized and discussed, particularly regarding manipulation using stem cells.
Links
EE2.3.20.0183, research and development projectName: Centrum experimentální biomedicíny
GAP304/11/1418, research and development projectName: Diferenciace lidských embryonálních kmenových buněk do odontogenních linií
Investor: Czech Science Foundation
NT11420, research and development projectName: Molekulární diagnostika hypodoncie a možnosti zubních autotransplantací
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