Odor Identification in Frontotemporal Lobar Degeneration
Subtypes

J 2014

Odor Identification in Frontotemporal Lobar Degeneration Subtypes

MAGEROVA, Hana, Martin VYHNALEK, Jan LACZO, Ross ANDEL, Irena REKTOROVÁ et. al.

Basic information

Original name

Odor Identification in Frontotemporal Lobar Degeneration Subtypes

Authors

MAGEROVA, Hana (203 Czech Republic), Martin VYHNALEK (203 Czech Republic), Jan LACZO (203 Czech Republic), Ross ANDEL (840 United States of America), Irena REKTOROVÁ (203 Czech Republic, guarantor, belonging to the institution), Alexandra KADLECOVA (203 Czech Republic), Martin BOJAR (203 Czech Republic) and Jakub HORT (203 Czech Republic)

Edition

American Journal of Alzheimer's Disease and other Dementias, Thousand Oaks, SAGE Publications Inc. 2014, 1533-3175

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.627

RIV identification code

RIV/00216224:14110/14:00078744

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1177/1533317514539033

UT WoS

000345335300017

Keywords in English

odor identification; behavioral variant frontotemporal dementia; primary nonfluent aphasia; semantic dementia; progressive supranuclear palsy; cognitive status

Abstract

V originále

Odor identification impairment is a feature of several neurodegenerative disorders. Although neurodegenerative changes in the frontotemporal lobar degeneration (FTLD) subtypes involve areas important for olfactory processing, data on olfactory function in these patients are limited. An 18-item, multiple-choice odor identification test developed at our memory clinic, the Motol Hospital smell test, was administered to 9 patients with behavioral variant frontotemporal dementia, 13 patients with the language variants, primary nonfluent aphasia (n = 7) and semantic dementia (n = 6), and 8 patients with progressive supranuclear palsy. Compared to the control group (n = 15), all FTLD subgroups showed significant impairment of odor identification (P < .05). The differences between the FTLD subgroups were not significant. No correlation between odor identification and neuropsychological tests results was found. Our data suggest that odor identification impairment is a symptom common to FTLD syndromes, and it seems to be based on olfactory structure damage rather than cognitive decline.

Citovat

MAGEROVA, Hana, Martin VYHNALEK, Jan LACZO, Ross ANDEL, Irena REKTOROVÁ, Alexandra KADLECOVA, Martin BOJAR and Jakub HORT. Odor Identification in Frontotemporal Lobar Degeneration Subtypes. American Journal of Alzheimer's Disease and other Dementias. Thousand Oaks: SAGE Publications Inc., 2014, vol. 29, No 8, p. 762-768. ISSN 1533-3175. Available from: https://dx.doi.org/10.1177/1533317514539033.

@article{1218844,
   author = {Magerova, Hana and Vyhnalek, Martin and Laczo, Jan and Andel, Ross and Rektorová, Irena and Kadlecova, Alexandra and Bojar, Martin and Hort, Jakub},
   article_location = {Thousand Oaks},
   article_number = {8},
   doi = {http://dx.doi.org/10.1177/1533317514539033},
   keywords = {odor identification; behavioral variant frontotemporal dementia; primary nonfluent aphasia; semantic dementia; progressive supranuclear palsy; cognitive status},
   language = {eng},
   issn = {1533-3175},
   journal = {American Journal of Alzheimer's Disease and other Dementias},
   title = {Odor Identification in Frontotemporal Lobar Degeneration Subtypes},
   volume = {29},
   year = {2014}
}

TY  - JOUR
ID  - 1218844
AU  - Magerova, Hana - Vyhnalek, Martin - Laczo, Jan - Andel, Ross - Rektorová, Irena - Kadlecova, Alexandra - Bojar, Martin - Hort, Jakub
PY  - 2014
TI  - Odor Identification in Frontotemporal Lobar Degeneration Subtypes
JF  - American Journal of Alzheimer's Disease and other Dementias
VL  - 29
IS  - 8
SP  - 762-768
EP  - 762-768
PB  - SAGE Publications Inc.
SN  - 15333175
KW  - odor identification
KW  - behavioral variant frontotemporal dementia
KW  - primary nonfluent aphasia
KW  - semantic dementia
KW  - progressive supranuclear palsy
KW  - cognitive status
N2  - Odor identification impairment is a feature of several neurodegenerative disorders. Although neurodegenerative changes in the frontotemporal lobar degeneration (FTLD) subtypes involve areas important for olfactory processing, data on olfactory function in these patients are limited. An 18-item, multiple-choice odor identification test developed at our memory clinic, the Motol Hospital smell test, was administered to 9 patients with behavioral variant frontotemporal dementia, 13 patients with the language variants, primary nonfluent aphasia (n = 7) and semantic dementia (n = 6), and 8 patients with progressive supranuclear palsy. Compared to the control group (n = 15), all FTLD subgroups showed significant impairment of odor identification (P < .05). The differences between the FTLD subgroups were not significant. No correlation between odor identification and neuropsychological tests results was found. Our data suggest that odor identification impairment is a symptom common to FTLD syndromes, and it seems to be based on olfactory structure damage rather than cognitive decline.
ER  -

MAGEROVA, Hana, Martin VYHNALEK, Jan LACZO, Ross ANDEL, Irena REKTOROVÁ, Alexandra KADLECOVA, Martin BOJAR and Jakub HORT. Odor Identification in Frontotemporal Lobar Degeneration Subtypes. \textit{American Journal of Alzheimer's Disease and other Dementias}. Thousand Oaks: SAGE Publications Inc., 2014, vol.~29, No~8, p.~762-768. ISSN~1533-3175. Available from: https://dx.doi.org/10.1177/1533317514539033.

Detailed Information on Publication Record