The chapter focuses on the communication skills of pupils with physical disabilities who attend a school for pupils with physical disabilities in the Republic of Baden-Württemberg in Germany. Briefly introduced the issue of social inclusion and physical disability, as defined by impaired communication ability of persons with disabilities and professionals who intervening in the context of a comprehensive approach to persons with disabilities and with difficulties in communication. The empirical part of the chapter provides the results of a qualitative research that was done in the form of two case studies of pupils with physical disabilities with regard to their communication skills.