Moesin and Radixin are downregulated by c-Myb in breast carcinomas

KNOPFOVÁ, Lucia, Petr BENEŠ, Michal MASAŘÍK, Pierre JURDIC and Jan ŠMARDA. Moesin and Radixin are downregulated by c-Myb in breast carcinomas. 2013.

Basic information

• Original name: Moesin and Radixin are downregulated by c-Myb in breast carcinomas
• Authors: KNOPFOVÁ, Lucia (203 Czech Republic, belonging to the institution), Petr BENEŠ (203 Czech Republic, belonging to the institution), Michal MASAŘÍK (203 Czech Republic), Pierre JURDIC (250 France) and Jan ŠMARDA (203 Czech Republic, guarantor, belonging to the institution).
• Edition: 2013.

Other information

• Original language: English
• Type of outcome: Conference abstract
• Field of Study: Genetics and molecular biology
• Country of publisher: Spain
• Confidentiality degree: is not subject to a state or trade secret
• RIV identification code: RIV/00216224:14310/13:00078966
• Organization unit: Faculty of Science
• Keywords in English: moesin; eadixin; Myb; breast carcinoma

Abstract

We described negative correlation between Myb and msan/rdx expression in human breast carcinoma cell line. we hypothesize that decreased expression of the ERM proteins by c-Myb might contribute to growth suppression and limited capacity of the myb-overexpressing breast tumors to form site-selective metastases.

Links

• EE2.4.31.0155, research and development project: Name: Partnerství a sítě pro spolupráci v experimentální biologii
• NT13441, research and development project: Name: Exprese proteinů rodiny Myb v adenokarcinomech tlustého střeva a vztah k jejich metastatickému potenciálu