Detailed Information on Publication Record
2014
Možnosti kontinuálního monitoringu průtoku krve mozkem v detekci vazospazmů u pacientů po těžkém subarachnoidálním krvácení
MRLIAN, A., Kamil ĎURIŠ, E. NEUMAN, Václav VYBÍHAL, Martin SMRČKA et. al.Basic information
Original name
Možnosti kontinuálního monitoringu průtoku krve mozkem v detekci vazospazmů u pacientů po těžkém subarachnoidálním krvácení
Name (in English)
Options for Continual Cerebral Blood Flow Monitoring to Detect Vasospasms in Patients after Severe Subarachnoid Haemorrhage
Authors
MRLIAN, A. (203 Czech Republic, guarantor), Kamil ĎURIŠ (203 Czech Republic, belonging to the institution), E. NEUMAN (203 Czech Republic), Václav VYBÍHAL (203 Czech Republic, belonging to the institution) and Martin SMRČKA (203 Czech Republic, belonging to the institution)
Edition
Česká a Slovenská neurologie a neurochirurgie, Praha, Česká lékařská společnost J.E.Purkyně, 2014, 1210-7859
Other information
Language
Czech
Type of outcome
Článek v odborném periodiku
Field of Study
30000 3. Medical and Health Sciences
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
Impact factor
Impact factor: 0.165
RIV identification code
RIV/00216224:14110/14:00078974
Organization unit
Faculty of Medicine
UT WoS
000336563200009
Keywords in English
subarachnoid haemorrhage; multimodal monitoring; cerebral blood flow
Tags
Tags
International impact, Reviewed
Změněno: 6/2/2015 14:30, Ing. Mgr. Věra Pospíšilíková
V originále
Z hlediska prognózy pacientů po ruptuře aneuryzmatu a vzniku subarachnoidálního krvácení je intenzivní péče stejně důležitá jako včasná diagnostika a ošetření aneuryzmatu. Vyšší morbidita a mortalita je typická u pacientů s klinickým stavem odpovídajícímu vyššímu stupni dle Hunta a Hesse. Multimodální monitoring by mohl umožnit časné detailnější zhodnocení skutečného klinického stavu pacientů a pomoci včas zahájit adekvátní terapii.
In English
Introduction: Intensive care seems to be as important for prognosis after ruptured aneurysm and subarachnoid haemorrhage as early diagnosis and treatment of the aneurysm. Higher morbidity and mortality is typical in patients with clinical status corresponding to a higher Hunt and Hess grade. Multimodal monitoring would allow early detailed assessment of the patient's actual clinical status and enable timely initiation of an appropriate therapy. Material and methods: A total number of 29 patients HH grade IV + V were monitored. Due to technical and procedural errors, 17 patients were finally analyzed. The objective was to measure the correlation between clinical status, outcome, tissue oxygen levels and TCD with respect to direct measurement of cerebral blood flow. Results: No statistically significant correlation was found between the mean values of CBF (for the entire monitoring period) and the HH grade, Fisher and GOS In the examined group. Correlation between CBF and PbtO2 varied widely between patients (r = 0.16-0.65). There was not significant correlation in the research sample between CBF and flow parameters of the main vessels (PSV, EDV, Vmean, p = NS for all parameters). Furthermore, no significant correlation was found in the research sample between CBF and resistivity and pulsatility indices (PI, RI, p = NS) but there was a trend towards indirect correlation between CBF and RI (r = -0.3844, p = 0.0786). Conclusion: Comprehensive monitoring of patients after subarachnoid haemorrhage provides a broad picture of the processes running in the damaged brain tissue and improves intensive treatment. However, direct measurement of CBF has, according to our findings, inconsistent value for the diagnosis of vasospasm and patient evaluation. Therefore, this cannot be used as a basis for therapy choices in these patients.