| DEMLOVÁ, Regina, Kristýna MELICHÁRKOVÁ, Zdeněk ŘEHÁK, Leoš KŘEN, Hana OŠLEJŠKOVÁ and Jaroslav ŠTĚRBA. Successful use of metronomic vinblastine and fluorothymidine pet imaging for the management of intramedullary spinal cord anaplastic oligoastrocytoma in a child. Current Oncology. Toronto: Multimed INC., 2014, vol. 21, No 6, p. "E790"-"E793", 4 pp. ISSN 1198-0052. Available from: https://dx.doi.org/10.3747/co.21.2147. |
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@article{1220489,
author = {Demlová, Regina and Melichárková, Kristýna and Řehák, Zdeněk and Křen, Leoš and Ošlejšková, Hana and Štěrba, Jaroslav},
article_location = {Toronto},
article_number = {6},
doi = {http://dx.doi.org/10.3747/co.21.2147},
keywords = {Biomarkers; Metronomic chemotherapy; Pediatric glioma; PET imaging; Vinblastine},
language = {eng},
issn = {1198-0052},
journal = {Current Oncology},
title = {Successful use of metronomic vinblastine and fluorothymidine pet imaging for the management of intramedullary spinal cord anaplastic oligoastrocytoma in a child},
volume = {21},
year = {2014}
}
TY - JOUR
ID - 1220489
AU - Demlová, Regina - Melichárková, Kristýna - Řehák, Zdeněk - Křen, Leoš - Ošlejšková, Hana - Štěrba, Jaroslav
PY - 2014
TI - Successful use of metronomic vinblastine and fluorothymidine pet imaging for the management of intramedullary spinal cord anaplastic oligoastrocytoma in a child
JF - Current Oncology
VL - 21
IS - 6
SP - "E790"-"E793"
EP - "E790"-"E793"
PB - Multimed INC.
SN - 11980052
KW - Biomarkers
KW - Metronomic chemotherapy
KW - Pediatric glioma
KW - PET imaging
KW - Vinblastine
N2 - Background: Children with high-grade glioma still have a poor prognosis despite the use of multimodal therapy including surgery, radiotherapy, and chemotherapy. New therapeutic strategies and methods evaluating such therapies are needed. Observation: Here we describe a child with anaplastic oligodendroglioma of the spinal cord who was unable to tolerate standard chemoradiotherapy and who had still-vital residual tumour during therapy. A good response was obtained with low-dose metronomic treatment containing vinblastine. The treatment was guided according to gradual response assessed using various positron-emission tomography tracers. Conclusions: Metronomic treatment guided by positron-emission tomography could be a reasonable option in some high-risk pediatric tumours.
ER -
DEMLOVÁ, Regina, Kristýna MELICHÁRKOVÁ, Zdeněk ŘEHÁK, Leoš KŘEN, Hana OŠLEJŠKOVÁ and Jaroslav ŠTĚRBA. Successful use of metronomic vinblastine and fluorothymidine pet imaging for the management of intramedullary spinal cord anaplastic oligoastrocytoma in a child. \textit{Current Oncology}. Toronto: Multimed INC., 2014, vol.~21, No~6, p.~''E790''-''E793'', 4 pp. ISSN~1198-0052. Available from: https://dx.doi.org/10.3747/co.21.2147.
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