KARA, Tomas, Pavel LEINVEBER, Michal VLASIN, Pavel JURAK, Miroslav NOVAK, Zdeněk NOVÁK, Jan CHRASTINA, Krzysztof CZECHOWICZ, Milos BELEHRAD and Samuel J. ASIRVATHAM. Endovascular brain intervention and mapping in a dog experimental model using magnetically-guided micro-catheter technology. Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic. Olomouc: Palacký University, 2014, vol. 158, No 2, p. 221-226. ISSN 1213-8118. Available from: https://dx.doi.org/10.5507/bp.2012.076.
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Basic information
Original name Endovascular brain intervention and mapping in a dog experimental model using magnetically-guided micro-catheter technology
Authors KARA, Tomas (203 Czech Republic), Pavel LEINVEBER (203 Czech Republic), Michal VLASIN (203 Czech Republic), Pavel JURAK (203 Czech Republic), Miroslav NOVAK (203 Czech Republic), Zdeněk NOVÁK (203 Czech Republic, belonging to the institution), Jan CHRASTINA (203 Czech Republic, guarantor, belonging to the institution), Krzysztof CZECHOWICZ (203 Czech Republic), Milos BELEHRAD (203 Czech Republic) and Samuel J. ASIRVATHAM (840 United States of America).
Edition Biomedical Papers of the Faculty of Medicine of Palacký University, Olomouc, Czech Republic, Olomouc, Palacký University, 2014, 1213-8118.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.200
RIV identification code RIV/00216224:14110/14:00079021
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.5507/bp.2012.076
UT WoS 000338628200010
Keywords in English central nervous system; magnetically-guided endovascular interventions; mapping; NIOBE
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 10/2/2015 16:20.
Abstract
Aim. Despite the substantial progress that has been achieved in interventional cardiology and cardiac electrophysiology, endovascular intervention for the diagnosis and treatment of central nervous system (CNS) disorders such as stroke, epilepsy and CNS malignancy is still limited, particularly due to highly tortuous nature of the cerebral arterial and venous system. Existing interventional devices and techniques enable only limited and complicated access especially into intra-cerebral vessels. The aim of this study was to develop a micro-catheter magnetically-guided technology specifically designed for endovascular intervention and mapping in deep CNS vascular structures. Methods. Mapping of electrical brain activity was performed via the venous system on an animal dog model with the support of the NIOBE II system. Results. A novel micro-catheter specially designed for endovascular interventions in the CNS, with the support of the NIOBE II technology, was able to reach safely deep intra-cerebral venous structures and map the electrical activity there. Such structures are not currently accessible using standard catheters. Conclusion. This is the first study demonstrating successful use of a new micro-catheter in combination with NIOBE II technology for endovascular intervention in the brain.
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