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@article{1227543, author = {Fojtová, Miloslava and Fajkus, Jiří}, article_location = {Basel}, article_number = {1-3}, doi = {http://dx.doi.org/10.1159/000360775}, keywords = {Chromatin; DNA methylation; Epigenetics; Histone modifications; Telomerase; Telomere; Telomeric transcripts}, language = {eng}, issn = {1424-8581}, journal = {Cytogenetic and Genome research}, title = {Epigenetic Regulation of Telomere Maintenance}, url = {http://www.karger.com/Article/Pdf/360775}, volume = {143}, year = {2014} }
TY - JOUR ID - 1227543 AU - Fojtová, Miloslava - Fajkus, Jiří PY - 2014 TI - Epigenetic Regulation of Telomere Maintenance JF - Cytogenetic and Genome research VL - 143 IS - 1-3 SP - 125-135 EP - 125-135 PB - Karger SN - 14248581 KW - Chromatin KW - DNA methylation KW - Epigenetics KW - Histone modifications KW - Telomerase KW - Telomere KW - Telomeric transcripts UR - http://www.karger.com/Article/Pdf/360775 L2 - http://www.karger.com/Article/Pdf/360775 N2 - As chromatin structures, telomeres undergo epigenetic regulation of their maintenance and function. In plants, these processes are likely of a higher complexity than in animals or yeasts, as exemplified by methylation of cytosines in plant telomeric DNA or reversible developmental regulation of plant telomerase. We highlight the dual role of telomeres from the epigenetic point of view: (i) as chromatin structures that are the subject of epigenetic regulation (e. g. DNA and histone modifications), and (ii) as chromosome domains acting themselves as epigenetic regulatory elements (e. g. in the telomere position effect). Possibly, some molecular tools (e. g. telomeric transcripts) are common to both these aspects of telomere epigenetics. We further discuss the justification for the classical textbook view of telomeres as heterochromatic structures. (C) 2014 S. Karger AG, Basel ER -
FOJTOVÁ, Miloslava and Jiří FAJKUS. Epigenetic Regulation of Telomere Maintenance. \textit{Cytogenetic and Genome research}. Basel: Karger, 2014, vol.~143, 1-3, p.~125-135. ISSN~1424-8581. Available from: https://dx.doi.org/10.1159/000360775.
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