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@article{1227543,
author = {Fojtová, Miloslava and Fajkus, Jiří},
article_location = {Basel},
article_number = {1-3},
doi = {http://dx.doi.org/10.1159/000360775},
keywords = {Chromatin; DNA methylation; Epigenetics; Histone modifications; Telomerase; Telomere; Telomeric transcripts},
language = {eng},
issn = {1424-8581},
journal = {Cytogenetic and Genome research},
title = {Epigenetic Regulation of Telomere Maintenance},
url = {http://www.karger.com/Article/Pdf/360775},
volume = {143},
year = {2014}
}
TY - JOUR
ID - 1227543
AU - Fojtová, Miloslava - Fajkus, Jiří
PY - 2014
TI - Epigenetic Regulation of Telomere Maintenance
JF - Cytogenetic and Genome research
VL - 143
IS - 1-3
SP - 125-135
EP - 125-135
PB - Karger
SN - 14248581
KW - Chromatin
KW - DNA methylation
KW - Epigenetics
KW - Histone modifications
KW - Telomerase
KW - Telomere
KW - Telomeric transcripts
UR - http://www.karger.com/Article/Pdf/360775
L2 - http://www.karger.com/Article/Pdf/360775
N2 - As chromatin structures, telomeres undergo epigenetic regulation of their maintenance and function. In plants, these processes are likely of a higher complexity than in animals or yeasts, as exemplified by methylation of cytosines in plant telomeric DNA or reversible developmental regulation of plant telomerase. We highlight the dual role of telomeres from the epigenetic point of view: (i) as chromatin structures that are the subject of epigenetic regulation (e. g. DNA and histone modifications), and (ii) as chromosome domains acting themselves as epigenetic regulatory elements (e. g. in the telomere position effect). Possibly, some molecular tools (e. g. telomeric transcripts) are common to both these aspects of telomere epigenetics. We further discuss the justification for the classical textbook view of telomeres as heterochromatic structures. (C) 2014 S. Karger AG, Basel
ER -
FOJTOVÁ, Miloslava and Jiří FAJKUS. Epigenetic Regulation of Telomere Maintenance. \textit{Cytogenetic and Genome research}. Basel: Karger, 2014, vol.~143, 1-3, p.~125-135. ISSN~1424-8581. Available from: https://dx.doi.org/10.1159/000360775.
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