If the cap fits, wear it: an overview of telomeric structures
over evolution

J 2014

If the cap fits, wear it: an overview of telomeric structures over evolution

FULCHER, N., E. DERBOVEN, S. VALUCHOVA and Karel ŘÍHA

Basic information

Original name

If the cap fits, wear it: an overview of telomeric structures over evolution

Authors

FULCHER, N. (40 Austria), E. DERBOVEN (40 Austria), S. VALUCHOVA (40 Austria) and Karel ŘÍHA (203 Czech Republic, guarantor, belonging to the institution)

Edition

Cellular and molecular life sciences, BASEL, BIRKHAUSER VERLAG AG, 2014, 1420-682X

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

Genetics and molecular biology

Country of publisher

Switzerland

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 5.808

RIV identification code

RIV/00216224:14740/14:00079175

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.1007/s00018-013-1469-z

UT WoS

000330963900006

Keywords in English

Telomeres; Telomerase; Chromosomes; Genome evolution; DNA repair; Retrotransposons

Abstract

V originále

Genome organization into linear chromosomes likely represents an important evolutionary innovation that has permitted the development of the sexual life cycle; this process has consequently advanced nuclear expansion and increased complexity of eukaryotic genomes. Chromosome linearity, however, poses a major challenge to the internal cellular machinery. The need to efficiently recognize and repair DNA double-strand breaks that occur as a consequence of DNA damage presents a constant threat to native chromosome ends known as telomeres. In this review, we present a comparative survey of various solutions to the end protection problem, maintaining an emphasis on DNA structure. This begins with telomeric structures derived from a subset of prokaryotes, mitochondria, and viruses, and will progress into the typical telomere structure exhibited by higher organisms containing TTAGG-like tandem sequences. We next examine non-canonical telomeres from Drosophila melanogaster, which comprise arrays of retrotransposons. Finally, we discuss telomeric structures in evolution and possible switches between canonical and non-canonical solutions to chromosome end protection.

Citovat

FULCHER, N., E. DERBOVEN, S. VALUCHOVA and Karel ŘÍHA. If the cap fits, wear it: an overview of telomeric structures over evolution. Cellular and molecular life sciences. BASEL: BIRKHAUSER VERLAG AG, 2014, vol. 71, No 5, p. 847-865. ISSN 1420-682X. Available from: https://dx.doi.org/10.1007/s00018-013-1469-z.

@article{1227578,
   author = {Fulcher, N. and Derboven, E. and Valuchova, S. and Říha, Karel},
   article_location = {BASEL},
   article_number = {5},
   doi = {http://dx.doi.org/10.1007/s00018-013-1469-z},
   keywords = {Telomeres; Telomerase; Chromosomes; Genome evolution; DNA repair; Retrotransposons},
   language = {eng},
   issn = {1420-682X},
   journal = {Cellular and molecular life sciences},
   title = {If the cap fits, wear it: an overview of telomeric structures over evolution},
   url = {http://download.springer.com/static/pdf/233/art%253A10.1007%252Fs00018-013-1469-z.pdf?auth66=1424688549_1693e66271e371331f99a2b7b64a52d7&ext=.pdf},
   volume = {71},
   year = {2014}
}

TY  - JOUR
ID  - 1227578
AU  - Fulcher, N. - Derboven, E. - Valuchova, S. - Říha, Karel
PY  - 2014
TI  - If the cap fits, wear it: an overview of telomeric structures over evolution
JF  - Cellular and molecular life sciences
VL  - 71
IS  - 5
SP  - 847-865
EP  - 847-865
PB  - BIRKHAUSER VERLAG AG
SN  - 1420682X
KW  - Telomeres
KW  - Telomerase
KW  - Chromosomes
KW  - Genome evolution
KW  - DNA repair
KW  - Retrotransposons
UR  - http://download.springer.com/static/pdf/233/art%253A10.1007%252Fs00018-013-1469-z.pdf?auth66=1424688549_1693e66271e371331f99a2b7b64a52d7&ext=.pdf
L2  - http://download.springer.com/static/pdf/233/art%253A10.1007%252Fs00018-013-1469-z.pdf?auth66=1424688549_1693e66271e371331f99a2b7b64a52d7&ext=.pdf
N2  - Genome organization into linear chromosomes likely represents an important evolutionary innovation that has permitted the development of the sexual life cycle; this process has consequently advanced nuclear expansion and increased complexity of eukaryotic genomes. Chromosome linearity, however, poses a major challenge to the internal cellular machinery. The need to efficiently recognize and repair DNA double-strand breaks that occur as a consequence of DNA damage presents a constant threat to native chromosome ends known as telomeres. In this review, we present a comparative survey of various solutions to the end protection problem, maintaining an emphasis on DNA structure. This begins with telomeric structures derived from a subset of prokaryotes, mitochondria, and viruses, and will progress into the typical telomere structure exhibited by higher organisms containing TTAGG-like tandem sequences. We next examine non-canonical telomeres from Drosophila melanogaster, which comprise arrays of retrotransposons. Finally, we discuss telomeric structures in evolution and possible switches between canonical and non-canonical solutions to chromosome end protection.
ER  -

FULCHER, N., E. DERBOVEN, S. VALUCHOVA and Karel ŘÍHA. If the cap fits, wear it: an overview of telomeric structures over evolution. \textit{Cellular and molecular life sciences}. BASEL: BIRKHAUSER VERLAG AG, 2014, vol.~71, No~5, p.~847-865. ISSN~1420-682X. Available from: https://dx.doi.org/10.1007/s00018-013-1469-z.

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