Dissociation in schizophrenia and borderline personality
disorder

J 2014

Dissociation in schizophrenia and borderline personality disorder

PĚČ, Ondřej, Petr BOB and Jiří RABOCH

Basic information

Original name

Dissociation in schizophrenia and borderline personality disorder

Authors

PĚČ, Ondřej (203 Czech Republic), Petr BOB (203 Czech Republic, guarantor, belonging to the institution) and Jiří RABOCH (203 Czech Republic)

Edition

Neuropsychiatric Disease and Treatment, New Zealand, Dove Medical Press, 2014, 1176-6328

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

New Zealand

Confidentiality degree

není předmětem státního či obchodního tajemství

References:

URL

Impact factor

Impact factor: 2.154 in 2013

RIV identification code

RIV/00216224:14740/14:00079327

Organization unit

Central European Institute of Technology

DOI

http://dx.doi.org/10.2147/NDT.S57627

UT WoS

000332838500001

Keywords in English

dissociation; stress-related symptoms; schizophrenia; borderline personality disorder; antipsychotic medication

Abstract

V originále

Background: Dissociation likely plays a key role in schizophrenia and borderline personality disorder (BPD), although empirical studies that compare specific manifestations of these symptoms in schizophrenia and BPD are rare. In this context, the purpose of this study was to compare the occurrence of dissociative and other psychopathological symptoms in these disorders, and to assess the possible influence of antipsychotic medication on the dissociative symptoms. Methods: We assessed 31 patients with schizophrenia and 36 patients with BPD. Dissociative symptoms were measured by the Dissociative Experiences Scale (DES), symptoms related to stress and traumatic experiences were assessed using the Trauma Symptom Checklist-40 (TSC-40), and other psychopathological symptoms were measured with the Health of the Nation Outcome Scales (HoNOS). We also assessed actual daily doses of antipsychotic medication in chlorpromazine equivalents in all participants. Results: The results show that symptoms of traumatic stress measured by the TSC-40 had significantly higher scores in the BPD group. The data also show that dissociative symptoms (DES) were significantly correlated with symptoms of traumatic stress (TSC-40) and with symptoms assessed by the HoNOS. Remarkably significant correlations were found between levels of antipsychotic medication and the DES and between antipsychotic medication and the depersonalization/derealization component of the DES in BPD patients. Conclusion: The results support an important role of dissociative processes in schizophrenia and BPD and suggest a significant relationship between manifestations of dissociative symptoms in BPD and antipsychotic medication.

Links

ED1.1.00/02.0068, research and development project

Name: CEITEC - central european institute of technology

Citovat

PĚČ, Ondřej, Petr BOB and Jiří RABOCH. Dissociation in schizophrenia and borderline personality disorder. Neuropsychiatric Disease and Treatment. New Zealand: Dove Medical Press, 2014, vol. 10, March, p. 487-491. ISSN 1176-6328. Available from: https://dx.doi.org/10.2147/NDT.S57627.

@article{1228863,
   author = {Pěč, Ondřej and Bob, Petr and Raboch, Jiří},
   article_location = {New Zealand},
   article_number = {March},
   doi = {http://dx.doi.org/10.2147/NDT.S57627},
   keywords = {dissociation; stress-related symptoms; schizophrenia; borderline personality disorder; antipsychotic medication},
   language = {eng},
   issn = {1176-6328},
   journal = {Neuropsychiatric Disease and Treatment},
   title = {Dissociation in schizophrenia and borderline personality disorder},
   url = {http://www.dovepress.com/dissociation-in-schizophrenia-and-borderline-personality-disorder-peer-reviewed-article-NDT},
   volume = {10},
   year = {2014}
}

TY  - JOUR
ID  - 1228863
AU  - Pěč, Ondřej - Bob, Petr - Raboch, Jiří
PY  - 2014
TI  - Dissociation in schizophrenia and borderline personality disorder
JF  - Neuropsychiatric Disease and Treatment
VL  - 10
IS  - March
SP  - 487-491
EP  - 487-491
PB  - Dove Medical Press
SN  - 11766328
KW  - dissociation
KW  - stress-related symptoms
KW  - schizophrenia
KW  - borderline personality disorder
KW  - antipsychotic medication
UR  - http://www.dovepress.com/dissociation-in-schizophrenia-and-borderline-personality-disorder-peer-reviewed-article-NDT
L2  - http://www.dovepress.com/dissociation-in-schizophrenia-and-borderline-personality-disorder-peer-reviewed-article-NDT
N2  - Background: Dissociation likely plays a key role in schizophrenia and borderline personality disorder (BPD), although empirical studies that compare specific manifestations of these symptoms in schizophrenia and BPD are rare. In this context, the purpose of this study was to compare the occurrence of dissociative and other psychopathological symptoms in these disorders, and to assess the possible influence of antipsychotic medication on the dissociative symptoms. Methods: We assessed 31 patients with schizophrenia and 36 patients with BPD. Dissociative symptoms were measured by the Dissociative Experiences Scale (DES), symptoms related to stress and traumatic experiences were assessed using the Trauma Symptom Checklist-40 (TSC-40), and other psychopathological symptoms were measured with the Health of the Nation Outcome Scales (HoNOS). We also assessed actual daily doses of antipsychotic medication in chlorpromazine equivalents in all participants. Results: The results show that symptoms of traumatic stress measured by the TSC-40 had significantly higher scores in the BPD group. The data also show that dissociative symptoms (DES) were significantly correlated with symptoms of traumatic stress (TSC-40) and with symptoms assessed by the HoNOS. Remarkably significant correlations were found between levels of antipsychotic medication and the DES and between antipsychotic medication and the depersonalization/derealization component of the DES in BPD patients. Conclusion: The results support an important role of dissociative processes in schizophrenia and BPD and suggest a significant relationship between manifestations of dissociative symptoms in BPD and antipsychotic medication.
ER  -

PĚČ, Ondřej, Petr BOB and Jiří RABOCH. Dissociation in schizophrenia and borderline personality disorder. \textit{Neuropsychiatric Disease and Treatment}. New Zealand: Dove Medical Press, 2014, vol.~10, March, p.~487-491. ISSN~1176-6328. Available from: https://dx.doi.org/10.2147/NDT.S57627.

Detailed Information on Publication Record