BEŠŠE, Lenka, Lenka SEDLAŘÍKOVÁ, Fedor KRYUKOV, Jana NEKVINDOVA, Lenka RADOVÁ, Martina ALMAŠI, Jana PELCOVA, Jiri MINARIK, Tomas PIKA, Zuzana PIKALOVA, Vlastimil SCUDLA, Marta KREJČÍ, Zdeněk ADAM, Luděk POUR, Roman HÁJEK and Sabina ŠEVČÍKOVÁ. Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia. American Journal of Hematology. Hoboken, USA: WILEY-BLACKWELL, vol. 90, No 3, p. "E51"-"E52", 2 pp. ISSN 0361-8609. doi:10.1002/ajh.23910. 2015. |
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@article{1228914, author = {Bešše, Lenka and Sedlaříková, Lenka and Kryukov, Fedor and Nekvindova, Jana and Radová, Lenka and Almaši, Martina and Pelcova, Jana and Minarik, Jiri and Pika, Tomas and Pikalova, Zuzana and Scudla, Vlastimil and Krejčí, Marta and Adam, Zdeněk and Pour, Luděk and Hájek, Roman and Ševčíková, Sabina}, article_location = {Hoboken, USA}, article_number = {3}, doi = {http://dx.doi.org/10.1002/ajh.23910}, keywords = {microRNA-320a; microRNA-320b; Waldenström macroglobulinemia}, language = {eng}, issn = {0361-8609}, journal = {American Journal of Hematology}, title = {Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia}, volume = {90}, year = {2015} }
TY - JOUR ID - 1228914 AU - Bešše, Lenka - Sedlaříková, Lenka - Kryukov, Fedor - Nekvindova, Jana - Radová, Lenka - Almaši, Martina - Pelcova, Jana - Minarik, Jiri - Pika, Tomas - Pikalova, Zuzana - Scudla, Vlastimil - Krejčí, Marta - Adam, Zdeněk - Pour, Luděk - Hájek, Roman - Ševčíková, Sabina PY - 2015 TI - Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia JF - American Journal of Hematology VL - 90 IS - 3 SP - "E51"-"E52" EP - "E51"-"E52" PB - WILEY-BLACKWELL SN - 03618609 KW - microRNA-320a KW - microRNA-320b KW - Waldenström macroglobulinemia N2 - IgM monoclonal gammopathies are a group of diseases characterized by increased level of IgM immunoglobulin produced by one clone of B cells. These diseases range trom benign (monoclonal gammopathy ot undetermined significance, MGUS) to malignant, such as Waldenstrom macroglobulinemia (WM) or to a lesser extent multiple myeloma (MM) [1,2]. The criteria that differentiate WM from IgM-MGUS are based on the extent of bone marrow (BM) involvement, amount of serum concentration of the M-proicin, presence or absence of symptomatic disease or more recently, MYD88 (L265P) or CXCR4 mutations [3-6]. Despite that, new criteria for the differential diagnosis between these conditions are still needed, circulating microRNAs (miRNAs) being one of them. Circulating miRNAs are present in different body fluids; they reflect physiological or pathologi cal conditions and can be used tor patient classification [7,8]. Thus, we aimed to investigate the ability of serum miRNAs to distinguish WM from IgM-MGUS as well as IgM-MM patients and healthy donors (HD). ER -
BEŠŠE, Lenka, Lenka SEDLAŘÍKOVÁ, Fedor KRYUKOV, Jana NEKVINDOVA, Lenka RADOVÁ, Martina ALMAŠI, Jana PELCOVA, Jiri MINARIK, Tomas PIKA, Zuzana PIKALOVA, Vlastimil SCUDLA, Marta KREJČÍ, Zdeněk ADAM, Luděk POUR, Roman HÁJEK and Sabina ŠEVČÍKOVÁ. Combination of serum microRNA-320a and microRNA-320b as a marker for Waldenström macroglobulinemia. \textit{American Journal of Hematology}. Hoboken, USA: WILEY-BLACKWELL, vol.~90, No~3, p.~''E51''-''E52'', 2 pp. ISSN~0361-8609. doi:10.1002/ajh.23910. 2015.
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