| BENEŠÍK, Martin, Radka DOPITOVÁ, Lubomír JANDA, Jiří DOŠKAŘ, Marek MOŠA, Josef BOŠTÍK and Roman PANTŮČEK. CHAP domain of tail-associated protein from phage 812 and its lytic activity against Staphylococcus aureus. Russian Journal of Infection and Immunity. Sankt Peterburg: InformMed, 2014, vol. 4, S1, p. 33. ISSN 2220-7619. |
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@article{1229241,
author = {Benešík, Martin and Dopitová, Radka and Janda, Lubomír and Doškař, Jiří and Moša, Marek and Boštík, Josef and Pantůček, Roman},
article_location = {Sankt Peterburg},
article_number = {S1},
language = {eng},
issn = {2220-7619},
journal = {Russian Journal of Infection and Immunity},
title = {CHAP domain of tail-associated protein from phage 812 and its lytic activity against Staphylococcus aureus},
url = {http://iimmun.ru/index.php/iimm},
volume = {4},
year = {2014}
}
TY - JOUR
ID - 1229241
AU - Benešík, Martin - Dopitová, Radka - Janda, Lubomír - Doškař, Jiří - Moša, Marek - Boštík, Josef - Pantůček, Roman
PY - 2014
TI - CHAP domain of tail-associated protein from phage 812 and its lytic activity against Staphylococcus aureus
JF - Russian Journal of Infection and Immunity
VL - 4
IS - S1
SP - 33
EP - 33
PB - InformMed
SN - 22207619
UR - http://iimmun.ru/index.php/iimm
N2 - The increasing number of pathogenic bacteria resistant to antimicrobial agents is a serious public health problem. Phage therapy appears to be a suitable alternative to antibiotics treatment. In history, it was envisaged to use bacteriophages as antimicrobial agents but recently, the research focus on phage encoded antimicrobial proteins. Bacteriophages produce lytic enzymes two times during their lytic cycle. In this study we focused on tail hydrolase of polyvalent staphylococcal bacteriophage 812, a member of SPO1-like viruses from family Myoviridae. This enzyme play role in the beginning of phage lytic cycle. It disturbs bacteria cell wall for injection of phage DNA into bacterial cell. This lytic enzyme can be possible use as antimicrobial agents against S. aureus bacterial cells.
ER -
BENEŠÍK, Martin, Radka DOPITOVÁ, Lubomír JANDA, Jiří DOŠKAŘ, Marek MOŠA, Josef BOŠTÍK and Roman PANTŮČEK. CHAP domain of tail-associated protein from phage 812 and its lytic activity against Staphylococcus aureus. \textit{Russian Journal of Infection and Immunity}. Sankt Peterburg: InformMed, 2014, vol.~4, S1, p.~33. ISSN~2220-7619.
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