Detailed Information on Publication Record
2015
Hybrid therapy in the management of atrial fibrillation
STÁREK, Zdeněk, František LEHAR, Jiří JEŽ, Jiří WOLF, Miroslav NOVÁK et. al.Basic information
Original name
Hybrid therapy in the management of atrial fibrillation
Authors
STÁREK, Zdeněk (203 Czech Republic, guarantor, belonging to the institution), František LEHAR (203 Czech Republic, belonging to the institution), Jiří JEŽ (203 Czech Republic, belonging to the institution), Jiří WOLF (203 Czech Republic, belonging to the institution) and Miroslav NOVÁK (203 Czech Republic, belonging to the institution)
Edition
Current Cardiology Reviews, San Francisco, Bentham Science Publishers B.V. 2015, 1573-403X
Other information
Language
English
Type of outcome
Článek v odborném periodiku
Field of Study
30201 Cardiac and Cardiovascular systems
Country of publisher
United States of America
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14110/15:00082500
Organization unit
Faculty of Medicine
UT WoS
000212845800011
Keywords in English
Atrial fibrillation; catheter ablation of arrhythmias; pharmacological antiarrhythmic therapy; hybrid therapy
Tags
Tags
International impact, Reviewed
Změněno: 2/3/2016 12:24, Ing. Mgr. Věra Pospíšilíková
Abstract
V originále
Atrial fibrillation is the most common sustained arrhythmia. Because of the sub-optimal outcomes and associated risks of medical therapy as well as the recent advances in non-pharmacologic strategies, a multitude of combined (hybrid) algorithms have been introduced that improve efficacy of standalone therapies while maintaining a high safety profile. Antiarrhythmic administration enhances success rate of electrical cardioversion. Catheter ablation of antiarrhythmic drug-induced typical atrial flutter may prevent recurrent atrial fibrillation. Through simple ablation in the right atrium, suppression of atrial fibrillation may be achieved in patients with previously ineffective antiarrhythmic therapy. Efficacy of complex catheter ablation in the left atrium is improved with antiarrhythmic drugs. Catheter ablation followed by permanent pacemaker implantation is an effective and safe treatment option for selected patients. Additional strategies include pacing therapies such as atrial pacing with permanent pacemakers, preventive pacing algorithms, and/or implantable dual-chamber defibrillators are available. Modern hybrid strategies combining both epicardial and endocardial approaches in order to create a complex set of radiofrequency lesions in the left atrium have demonstrated a high rate of success and warrant further research. Hybrid therapy for atrial fibrillation reviews history of development of non-pharmacological treatment strategies and outlines avenues of ongoing research in this field.