Other formats:
BibTeX
LaTeX
RIS
@inbook{1297109,
author = {Martinkovic, L. and Hecimovic, H. and Sulc, V. and Mareček, Radek and Marusič, Petr},
address = {SAN DIEGO},
booktitle = {International Review of Neurobiology},
doi = {http://dx.doi.org/10.1016/B978-0-12-418693-4.00010-8},
edition = {114},
editor = {Jiruska P.},
keywords = {TEMPORAL-LOBE EPILEPSY; POSITRON-EMISSION-TOMOGRAPHY; VOXEL-BASED MORPHOMETRY; GENERALIZED TONICCLONIC SEIZURES},
howpublished = {tištěná verze "print"},
language = {eng},
location = {SAN DIEGO},
isbn = {978-0-12-418693-4},
pages = {245-278},
publisher = {ELSEVIER ACADEMIC PRESS INC},
title = {Modern Techniques of Epileptic Focus Localization},
url = {http://www.sciencedirect.com/science/article/pii/B9780124186934000108},
year = {2014}
}
TY - CHAP
ID - 1297109
AU - Martinkovic, L. - Hecimovic, H. - Sulc, V. - Mareček, Radek - Marusič, Petr
PY - 2014
TI - Modern Techniques of Epileptic Focus Localization
VL - Modern Concepts of Focal Epileptic Networks
PB - ELSEVIER ACADEMIC PRESS INC
CY - SAN DIEGO
SN - 9780124186934
KW - TEMPORAL-LOBE EPILEPSY
KW - POSITRON-EMISSION-TOMOGRAPHY
KW - VOXEL-BASED MORPHOMETRY
KW - GENERALIZED TONICCLONIC SEIZURES
UR - http://www.sciencedirect.com/science/article/pii/B9780124186934000108
L2 - http://www.sciencedirect.com/science/article/pii/B9780124186934000108
N2 - A clear concept of epileptic zones remains of high clinical relevance in presurgical evaluation of refractory epilepsy patients and in resection planning. Recent advances in understanding how each of the epileptic zones is functionally organized strengthened the importance of the network concept. It has been shown that neuronal networks underlying the individual epileptic zone may involve multiple brain structures with complex interactions between them. The network concept has impact not only for better understanding of pathophysiology of partial epilepsy but also for clinical practice, particularly for epilepsy surgery. This review examines recent reports on the use of advanced imaging techniques which enable to map the epileptic zones and their structural and functional organization. Magnetic resonance postprocessing substantially improved the accuracy in detection of the epileptogenic lesions. The seizure-onset zone is primarily determined by electrophysiology but can also be localized using single photon emission computed tomography. The functional deficit zone is commonly assessed by a number of tests including methods of functional neuroimaging (positron emission tomography) which can delineate hypometabolic cortical areas and subcortical structures. Hemodynamic fluctuations associated with interictal epileptiform discharges can be detected by novel functional magnetic resonance technique which is nowadays widely used for the irritative zone localization. These techniques open new prospect for epilepsy surgery in patients who were previously considered as not suitable candidates of surgical treatment.
ER -
MARTINKOVIC, L., H. HECIMOVIC, V. SULC, Radek MAREČEK and Petr MARUSIČ. Modern Techniques of Epileptic Focus Localization. In Jiruska P. \textit{International Review of Neurobiology}. 114th ed. SAN DIEGO: ELSEVIER ACADEMIC PRESS INC, 2014, p.~245-278. Modern Concepts of Focal Epileptic Networks. ISBN~978-0-12-418693-4. Available from: https://dx.doi.org/10.1016/B978-0-12-418693-4.00010-8.
|
