REKTOR, Ivan and Irena REKTOROVÁ. Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease. Online. Movement Disorders. Hoboken, USA: WILEY-BLACKWELL, 2011, vol. 26, No 7, p. 1363. ISSN 0885-3185. Available from: https://dx.doi.org/10.1002/mds.23444. [citováno 2024-04-23]
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Basic information
Original name Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease
Authors REKTOR, Ivan (203 Czech Republic, guarantor, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, belonging to the institution)
Edition Movement Disorders, Hoboken, USA, WILEY-BLACKWELL, 2011, 0885-3185.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30000 3. Medical and Health Sciences
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 4.505
RIV identification code RIV/00216224:14110/11:00080228
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1002/mds.23444
UT WoS 000291863600036
Keywords in English Parkinson's Disease; Pathology of Vessels
Tags International impact, Reviewed
Changed by Changed by: Soňa Böhmová, učo 232884. Changed: 20/5/2015 10:12.
Abstract
We have read with interest the study by Santangelo et al.,1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsychological profile of patients affected by Parkinsonism and vascular lesions to that of patients with Parkinson's disease (PD) without vascular lesions. The conclusion was that “regardless of the presence of dopaminergic denervation, cerebrovascular lesions … have an important effect in determining early onset and severity of cognitive impairment in patients with parkinsonism”. We agree with the authors that a comorbid cerebrovascular disease (CVD) may have an important impact on impairment of cognitive functions in patients with PD. In this aspect, the PD patients are not fundamentally different from patients without Parkinsonism.
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