J 2011

Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease

REKTOR, Ivan and Irena REKTOROVÁ

Basic information

Original name

Pathology of Vessels Supplying the Brain in Patients with Parkinson's Disease

Authors

REKTOR, Ivan (203 Czech Republic, guarantor, belonging to the institution) and Irena REKTOROVÁ (203 Czech Republic, belonging to the institution)

Edition

Movement Disorders, Hoboken, USA, WILEY-BLACKWELL, 2011, 0885-3185

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30000 3. Medical and Health Sciences

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 4.505

RIV identification code

RIV/00216224:14110/11:00080228

Organization unit

Faculty of Medicine

DOI

UT WoS

000291863600036

Keywords in English

Parkinson's Disease; Pathology of Vessels

Tags

International impact, Reviewed
Změněno: 20/5/2015 10:12, Soňa Böhmová

Abstract

V originále

We have read with interest the study by Santangelo et al.,1 reporting the role of vascular pathology in the neuropsychological profile of parkinsonian patients. The authors evaluated whether the brain's vascular lesion load is associated with neuropsychological variables. They compared the neuropsychological profile of patients affected by Parkinsonism and vascular lesions to that of patients with Parkinson's disease (PD) without vascular lesions. The conclusion was that “regardless of the presence of dopaminergic denervation, cerebrovascular lesions … have an important effect in determining early onset and severity of cognitive impairment in patients with parkinsonism”. We agree with the authors that a comorbid cerebrovascular disease (CVD) may have an important impact on impairment of cognitive functions in patients with PD. In this aspect, the PD patients are not fundamentally different from patients without Parkinsonism.