Isolated heart models: cardiovascular system studies and
technological advances

J 2015

Isolated heart models: cardiovascular system studies and technological advances

OLEJNÍČKOVÁ, Veronika, Marie NOVÁKOVÁ and Ivo PROVAZNIK

Basic information

Original name

Isolated heart models: cardiovascular system studies and technological advances

Authors

OLEJNÍČKOVÁ, Veronika (203 Czech Republic, belonging to the institution), Marie NOVÁKOVÁ (203 Czech Republic, belonging to the institution) and Ivo PROVAZNIK (203 Czech Republic)

Edition

Medical & Biological Engineering & Computing, Heidelberg, Springer Heidelberg, 2015, 0140-0118

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30105 Physiology

Country of publisher

Germany

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.797

RIV identification code

RIV/00216224:14110/15:00080810

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s11517-015-1270-2

UT WoS

000354638900009

Keywords in English

Isolated heart; Langendorff · Neely; Monophasic action potential; Electrogram

Abstract

V originále

Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.

Links

GAP102/12/2034, research and development project

Name: Analýza vztahu mezi elektrickými ději a průtokem krve u srdečních komor

Investor: Czech Science Foundation

Citovat

OLEJNÍČKOVÁ, Veronika, Marie NOVÁKOVÁ and Ivo PROVAZNIK. Isolated heart models: cardiovascular system studies and technological advances. Medical & Biological Engineering & Computing. Heidelberg: Springer Heidelberg, 2015, vol. 53, No 7, p. 669-678. ISSN 0140-0118. Available from: https://dx.doi.org/10.1007/s11517-015-1270-2.

@article{1299771,
   author = {Olejníčková, Veronika and Nováková, Marie and Provaznik, Ivo},
   article_location = {Heidelberg},
   article_number = {7},
   doi = {http://dx.doi.org/10.1007/s11517-015-1270-2},
   keywords = {Isolated heart; Langendorff · Neely; Monophasic action potential; Electrogram},
   language = {eng},
   issn = {0140-0118},
   journal = {Medical & Biological Engineering & Computing},
   title = {Isolated heart models: cardiovascular system studies and technological advances},
   volume = {53},
   year = {2015}
}

TY  - JOUR
ID  - 1299771
AU  - Olejníčková, Veronika - Nováková, Marie - Provaznik, Ivo
PY  - 2015
TI  - Isolated heart models: cardiovascular system studies and technological advances
JF  - Medical & Biological Engineering & Computing
VL  - 53
IS  - 7
SP  - 669-678
EP  - 669-678
PB  - Springer Heidelberg
SN  - 01400118
KW  - Isolated heart
KW  - Langendorff · Neely
KW  - Monophasic action potential
KW  - Electrogram
N2  - Isolated heart model is a relevant tool for cardiovascular system studies. It represents a highly reproducible model for studying broad spectrum of biochemical, physiological, morphological, and pharmaceutical parameters, including analysis of intrinsic heart mechanics, metabolism, and coronary vascular response. Results obtained in this model are under no influence of other organ systems, plasma concentration of hormones or ions and influence of autonomic nervous system. The review describes various isolated heart models, the modes of heart perfusion, and advantages and limitations of various experimental setups. It reports the improvements of perfusion setup according to Langendorff introduced by the authors.
ER  -

OLEJNÍČKOVÁ, Veronika, Marie NOVÁKOVÁ and Ivo PROVAZNIK. Isolated heart models: cardiovascular system studies and technological advances. \textit{Medical \&{} Biological Engineering \&{} Computing}. Heidelberg: Springer Heidelberg, 2015, vol.~53, No~7, p.~669-678. ISSN~0140-0118. Available from: https://dx.doi.org/10.1007/s11517-015-1270-2.

Detailed Information on Publication Record