The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions

PILAŘOVÁ, Iveta, Ondřej LASKAFELD, Přemysl LUBAL and Libuše TRNKOVÁ. The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions. Online. In 17th Topical Meeting of the International Society of Electrochemistry. 1st ed. France: International Society of Electrochemistry, 2015, p. 201-201.

Basic information

• Original name: The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions
• Authors: PILAŘOVÁ, Iveta, Ondřej LASKAFELD, Přemysl LUBAL and Libuše TRNKOVÁ.
• Edition: 1. vyd. France, 17th Topical Meeting of the International Society of Electrochemistry, p. 201-201, 1 pp. 2015.
• Publisher: International Society of Electrochemistry

Other information

• Original language: English
• Type of outcome: Proceedings paper
• Field of Study: 10403 Physical chemistry
• Country of publisher: Czech Republic
• Confidentiality degree: is not subject to a state or trade secret
• Publication form: electronic version available online
• Organization unit: Faculty of Science
• Keywords (in Czech): benzylaminopurin; ionty mědi; PeGE; linear sweep voltametrie; cyklická voltametrie; eliminační voltametrická procedura
• Keywords in English: benzylaminopurine; copper ions; PeGE; linear sweep voltammetry; cyclic voltammetry; elimination voltammetric procedure
• Tags: NZ

Abstract

Benzylaminopurine (6-BAP), the most important cytokinin of adenine type, and its methoxylated and chlorinated derivatives in the form of dinuclear complexes with metal ions are a hot topic in biuomedicine. BAPs are investigated as possible enzyme inhibitors, anti-bacterial, anti-viral and anti-tumor agents. The theoretical investigations of some 6-benzylaminopurine derivatives together with X-ray, FT-IR and Raman spectroscopy characterization were performed by Cajan et al. The aim of our contribution is the systematic voltammetric study of the oxidation processes of methoxylated and chlorinated (in positions 2', 3' and 4' of benzene ring) derivatives of 6-BAP. Voltammetric studies using LSV and CV techniques were performed in buffered H2O/Ch3OH solutions (pH 3.18 - 6.8; 2% v/v CH3OH) utilizing a pencil graphite electrode (PeGE - Tombow, Japan), the surface of which was in-situ modified with monovalent copper. The sensing is based on the formation of Cu(I)-BAP surface compexes which are subsequently stripped out from the electrode by potential scan. The stripping mode enables higher sensitivity in detecting the oxidation signals of all BAP derivatives. Where appropriate,voltammetric data were treated with Elimination voltammetric procedure - EVP to obtain details of the studied electrochemical transformations. The electrochemical experiments were complemented with UV/VIS spectral experiments, electron densities on atoms and precise determinations of the HOMO levels of the studied purine derivatives were obtained by quantum chemistry calculations.

Links

• CZ.1.05/1.1.00/02.0068, interní kód MU: Name: CEITEC - středoevropský technologický institut (Acronym: CEITEC)

Investor: Ministry of Education, Youth and Sports of the CR, CEITEC - Central European Institute of Technology, 1.1 European Centres of Excellence

• LH13053, research and development project: Name: Chemická a elektrochemická analýza purinových derivátů a jejich komplexů s mědí (Acronym: CECAP)

Investor: Ministry of Education, Youth and Sports of the CR

• MUNI/A/0972/2013, interní kód MU: Name: Vývoj metod a instrumentace pro analýzu biologicky významných látek 2014 (Acronym: MIAB)

Investor: Masaryk University, Category A

• MUNI/A/1452/2014, interní kód MU: Name: Vývoj metod a instrumentace pro analýzu biologicky významných látek 2015

Investor: Masaryk University, Category A