The Oxidation Processes of Benzylaminopurines at Pencil
Graphite Electrodes Modified by Monovalent Copper Ions

D 2015

The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions

PILAŘOVÁ, Iveta, Ondřej LASKAFELD, Přemysl LUBAL and Libuše TRNKOVÁ

Basic information

Original name

The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions

Authors

PILAŘOVÁ, Iveta, Ondřej LASKAFELD, Přemysl LUBAL and Libuše TRNKOVÁ

Edition

1. vyd. France, 17th Topical Meeting of the International Society of Electrochemistry, p. 201-201, 1 pp. 2015

Publisher

International Society of Electrochemistry

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10403 Physical chemistry

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

electronic version available online

Organization unit

Faculty of Science

Keywords (in Czech)

benzylaminopurin; ionty mědi; PeGE; linear sweep voltametrie; cyklická voltametrie; eliminační voltametrická procedura

Keywords in English

benzylaminopurine; copper ions; PeGE; linear sweep voltammetry; cyclic voltammetry; elimination voltammetric procedure

Abstract

V originále

Benzylaminopurine (6-BAP), the most important cytokinin of adenine type, and its methoxylated and chlorinated derivatives in the form of dinuclear complexes with metal ions are a hot topic in biuomedicine. BAPs are investigated as possible enzyme inhibitors, anti-bacterial, anti-viral and anti-tumor agents. The theoretical investigations of some 6-benzylaminopurine derivatives together with X-ray, FT-IR and Raman spectroscopy characterization were performed by Cajan et al. The aim of our contribution is the systematic voltammetric study of the oxidation processes of methoxylated and chlorinated (in positions 2', 3' and 4' of benzene ring) derivatives of 6-BAP. Voltammetric studies using LSV and CV techniques were performed in buffered H2O/Ch3OH solutions (pH 3.18 - 6.8; 2% v/v CH3OH) utilizing a pencil graphite electrode (PeGE - Tombow, Japan), the surface of which was in-situ modified with monovalent copper. The sensing is based on the formation of Cu(I)-BAP surface compexes which are subsequently stripped out from the electrode by potential scan. The stripping mode enables higher sensitivity in detecting the oxidation signals of all BAP derivatives. Where appropriate,voltammetric data were treated with Elimination voltammetric procedure - EVP to obtain details of the studied electrochemical transformations. The electrochemical experiments were complemented with UV/VIS spectral experiments, electron densities on atoms and precise determinations of the HOMO levels of the studied purine derivatives were obtained by quantum chemistry calculations.

Links

CZ.1.05/1.1.00/02.0068, interní kód MU

Name: CEITEC - středoevropský technologický institut (Acronym: CEITEC)

Investor: Ministry of Education, Youth and Sports of the CR, CEITEC - Central European Institute of Technology, 1.1 European Centres of Excellence

LH13053, research and development project

Name: Chemická a elektrochemická analýza purinových derivátů a jejich komplexů s mědí (Acronym: CECAP)

Investor: Ministry of Education, Youth and Sports of the CR

MUNI/A/0972/2013, interní kód MU

Name: Vývoj metod a instrumentace pro analýzu biologicky významných látek 2014 (Acronym: MIAB)

Investor: Masaryk University, Category A

MUNI/A/1452/2014, interní kód MU

Name: Vývoj metod a instrumentace pro analýzu biologicky významných látek 2015

Investor: Masaryk University, Category A

Citovat

PILAŘOVÁ, Iveta, Ondřej LASKAFELD, Přemysl LUBAL and Libuše TRNKOVÁ. The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions. Online. In 17th Topical Meeting of the International Society of Electrochemistry. 1st ed. France: International Society of Electrochemistry, 2015, p. 201-201.

@inproceedings{1300725,
   author = {Pilařová, Iveta and Laskafeld, Ondřej and Lubal, Přemysl and Trnková, Libuše},
   address = {France},
   booktitle = {17th Topical Meeting of the International Society of Electrochemistry},
   edition = {1.},
   keywords = {benzylaminopurine; copper ions; PeGE; linear sweep voltammetry; cyclic voltammetry; elimination voltammetric procedure},
   howpublished = {elektronická verze "online"},
   language = {eng},
   location = {France},
   note = {Nepřenášet do RIV - není na WoS ani Scopus, neodpovídá definici druhů výsledků dle M17+},
   pages = {201-201},
   publisher = {International Society of Electrochemistry},
   title = {The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions},
   year = {2015}
}

TY  - JOUR
ID  - 1300725
AU  - Pilařová, Iveta - Laskafeld, Ondřej - Lubal, Přemysl - Trnková, Libuše
PY  - 2015
TI  - The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions
PB  - International Society of Electrochemistry
CY  - France
N1  - Nepřenášet do RIV - není na WoS ani Scopus, neodpovídá definici druhů výsledků dle M17+
KW  - benzylaminopurine
KW  - copper ions
KW  - PeGE
KW  - linear sweep voltammetry
KW  - cyclic voltammetry
KW  - elimination voltammetric procedure
N2  - Benzylaminopurine (6-BAP), the most important cytokinin of adenine type, and its methoxylated and chlorinated derivatives in the form of dinuclear complexes with metal ions are a hot topic in biuomedicine. BAPs are investigated as possible enzyme inhibitors, anti-bacterial, anti-viral and anti-tumor agents. The theoretical investigations of some 6-benzylaminopurine derivatives together with X-ray, FT-IR and Raman spectroscopy characterization were performed by Cajan et al. The aim of our contribution is the systematic voltammetric study of the oxidation processes of methoxylated and chlorinated (in positions 2', 3' and 4' of benzene ring) derivatives of 6-BAP. Voltammetric studies using LSV and CV techniques were performed in buffered H2O/Ch3OH solutions (pH 3.18 - 6.8; 2% v/v CH3OH) utilizing a pencil graphite electrode (PeGE - Tombow, Japan), the surface of which was in-situ modified with monovalent copper. The sensing is based on the formation of Cu(I)-BAP surface compexes which are subsequently stripped out from the electrode by potential scan. The stripping mode enables higher sensitivity in detecting the oxidation signals of all BAP derivatives. Where appropriate,voltammetric data were treated with Elimination voltammetric procedure - EVP to obtain details of the studied electrochemical transformations. The electrochemical experiments were complemented with UV/VIS spectral experiments, electron densities on atoms and precise determinations of the HOMO levels of the studied purine derivatives were obtained by quantum chemistry calculations.
ER  -

PILAŘOVÁ, Iveta, Ondřej LASKAFELD, Přemysl LUBAL and Libuše TRNKOVÁ. The Oxidation Processes of Benzylaminopurines at Pencil Graphite Electrodes Modified by Monovalent Copper Ions. Online. In \textit{17th Topical Meeting of the International Society of Electrochemistry}. 1st ed. France: International Society of Electrochemistry, 2015, p.~201-201.

Detailed Information on Publication Record