Fertility status of Hodgkin lymphoma patients treated with
chemotherapy and adjuvant gonadotropin-releasing hormone
analogues

J 2015

Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues

HUSER, Martin, Lenka ŠMARDOVÁ, Petr JANKŮ, Igor CRHA, Jana ŽÁKOVÁ et. al.

Basic information

Original name

Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues

Authors

HUSER, Martin (203 Czech Republic, guarantor, belonging to the institution), Lenka ŠMARDOVÁ (203 Czech Republic, belonging to the institution), Petr JANKŮ (203 Czech Republic, belonging to the institution), Igor CRHA (203 Czech Republic, belonging to the institution), Jana ŽÁKOVÁ (203 Czech Republic, belonging to the institution), Petr ŠTOURAČ (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Jiří MAYER (203 Czech Republic, belonging to the institution) and Pavel VENTRUBA (203 Czech Republic, belonging to the institution)

Edition

Journal of Assisted Reproduction and Genetics, New York, Springer, 2015, 1058-0468

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30214 Obstetrics and gynaecology

Country of publisher

United States of America

Confidentiality degree

není předmětem státního či obchodního tajemství

Impact factor

Impact factor: 1.858

RIV identification code

RIV/00216224:14110/15:00083094

Organization unit

Faculty of Medicine

DOI

http://dx.doi.org/10.1007/s10815-015-0452-z

UT WoS

000360547300006

Keywords in English

Chemotherapy; Hodgkin lymphoma; Gonadotropin-releasing hormone analogues; Fertility; Pregnancy

Abstract

V originále

Purpose Aim of this prospective observational study was to analyze fertility status of Hodgkin lymphoma (HL) patients treated with different types of chemotherapy while receiving GnRH analogues to preserve ovarian function. Methods Fertility status was assessed among 108 females in reproductive age treated by curative chemotherapy for freshly diagnosed HL between 2005 and 2010 in university-based tertiary fertility and oncology center. All patients received GnRH analogues during chemotherapy to preserve their ovarian function. Their reproductive functions were assessed by follicle-stimulating hormone (FSH) measurement and pregnancy achievement. Ovarian function was determined separately in three groups with increasing gonadotoxicity of chemotherapy.

Citovat

HUSER, Martin, Lenka ŠMARDOVÁ, Petr JANKŮ, Igor CRHA, Jana ŽÁKOVÁ, Petr ŠTOURAČ, Jiří JARKOVSKÝ, Jiří MAYER and Pavel VENTRUBA. Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues. Journal of Assisted Reproduction and Genetics. New York: Springer, 2015, vol. 32, No 8, p. 1187-1193. ISSN 1058-0468. Available from: https://dx.doi.org/10.1007/s10815-015-0452-z.

@article{1300731,
   author = {Huser, Martin and Šmardová, Lenka and Janků, Petr and Crha, Igor and Žáková, Jana and Štourač, Petr and Jarkovský, Jiří and Mayer, Jiří and Ventruba, Pavel},
   article_location = {New York},
   article_number = {8},
   doi = {http://dx.doi.org/10.1007/s10815-015-0452-z},
   keywords = {Chemotherapy; Hodgkin lymphoma; Gonadotropin-releasing hormone analogues; Fertility; Pregnancy},
   language = {eng},
   issn = {1058-0468},
   journal = {Journal of Assisted Reproduction and Genetics},
   title = {Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues},
   volume = {32},
   year = {2015}
}

TY  - JOUR
ID  - 1300731
AU  - Huser, Martin - Šmardová, Lenka - Janků, Petr - Crha, Igor - Žáková, Jana - Štourač, Petr - Jarkovský, Jiří - Mayer, Jiří - Ventruba, Pavel
PY  - 2015
TI  - Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues
JF  - Journal of Assisted Reproduction and Genetics
VL  - 32
IS  - 8
SP  - 1187-1193
EP  - 1187-1193
PB  - Springer
SN  - 10580468
KW  - Chemotherapy
KW  - Hodgkin lymphoma
KW  - Gonadotropin-releasing hormone analogues
KW  - Fertility
KW  - Pregnancy
N2  - Purpose Aim of this prospective observational study was to analyze fertility status of Hodgkin lymphoma (HL) patients treated with different types of chemotherapy while receiving GnRH analogues to preserve ovarian function. Methods Fertility status was assessed among 108 females in reproductive age treated by curative chemotherapy for freshly diagnosed HL between 2005 and 2010 in university-based tertiary fertility and oncology center. All patients received GnRH analogues during chemotherapy to preserve their ovarian function. Their reproductive functions were assessed by follicle-stimulating hormone (FSH) measurement and pregnancy achievement. Ovarian function was determined separately in three groups with increasing gonadotoxicity of chemotherapy.
ER  -

HUSER, Martin, Lenka ŠMARDOVÁ, Petr JANKŮ, Igor CRHA, Jana ŽÁKOVÁ, Petr ŠTOURAČ, Jiří JARKOVSKÝ, Jiří MAYER and Pavel VENTRUBA. Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues. \textit{Journal of Assisted Reproduction and Genetics}. New York: Springer, 2015, vol.~32, No~8, p.~1187-1193. ISSN~1058-0468. Available from: https://dx.doi.org/10.1007/s10815-015-0452-z.

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