HUSER, Martin, Lenka ŠMARDOVÁ, Petr JANKŮ, Igor CRHA, Jana ŽÁKOVÁ, Petr ŠTOURAČ, Jiří JARKOVSKÝ, Jiří MAYER and Pavel VENTRUBA. Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues. Journal of Assisted Reproduction and Genetics. New York: Springer, 2015, vol. 32, No 8, p. 1187-1193. ISSN 1058-0468. Available from: https://dx.doi.org/10.1007/s10815-015-0452-z.
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Basic information
Original name Fertility status of Hodgkin lymphoma patients treated with chemotherapy and adjuvant gonadotropin-releasing hormone analogues
Authors HUSER, Martin (203 Czech Republic, guarantor, belonging to the institution), Lenka ŠMARDOVÁ (203 Czech Republic, belonging to the institution), Petr JANKŮ (203 Czech Republic, belonging to the institution), Igor CRHA (203 Czech Republic, belonging to the institution), Jana ŽÁKOVÁ (203 Czech Republic, belonging to the institution), Petr ŠTOURAČ (203 Czech Republic, belonging to the institution), Jiří JARKOVSKÝ (203 Czech Republic, belonging to the institution), Jiří MAYER (203 Czech Republic, belonging to the institution) and Pavel VENTRUBA (203 Czech Republic, belonging to the institution).
Edition Journal of Assisted Reproduction and Genetics, New York, Springer, 2015, 1058-0468.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 30214 Obstetrics and gynaecology
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 1.858
RIV identification code RIV/00216224:14110/15:00083094
Organization unit Faculty of Medicine
Doi http://dx.doi.org/10.1007/s10815-015-0452-z
UT WoS 000360547300006
Keywords in English Chemotherapy; Hodgkin lymphoma; Gonadotropin-releasing hormone analogues; Fertility; Pregnancy
Tags EL OK
Tags International impact, Reviewed
Changed by Changed by: Ing. Mgr. Věra Pospíšilíková, učo 9005. Changed: 28/4/2016 13:22.
Abstract
Purpose Aim of this prospective observational study was to analyze fertility status of Hodgkin lymphoma (HL) patients treated with different types of chemotherapy while receiving GnRH analogues to preserve ovarian function. Methods Fertility status was assessed among 108 females in reproductive age treated by curative chemotherapy for freshly diagnosed HL between 2005 and 2010 in university-based tertiary fertility and oncology center. All patients received GnRH analogues during chemotherapy to preserve their ovarian function. Their reproductive functions were assessed by follicle-stimulating hormone (FSH) measurement and pregnancy achievement. Ovarian function was determined separately in three groups with increasing gonadotoxicity of chemotherapy.
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