D 2015

Compact Representation of Photosynthesis Dynamics by Rule-based Models

BRIM, Luboš, Juraj NIŽNAN and David ŠAFRÁNEK

Basic information

Original name

Compact Representation of Photosynthesis Dynamics by Rule-based Models

Authors

BRIM, Luboš (203 Czech Republic, belonging to the institution), Juraj NIŽNAN (703 Slovakia, belonging to the institution) and David ŠAFRÁNEK (203 Czech Republic, guarantor, belonging to the institution)

Edition

316. vyd. Neuveden, 5th International Workshop on Static Analysis and Systems Biology (SASB 2014), p. 17-27, 11 pp. 2015

Publisher

Elsevier

Other information

Language

English

Type of outcome

Stať ve sborníku

Field of Study

10201 Computer sciences, information science, bioinformatics

Country of publisher

Czech Republic

Confidentiality degree

není předmětem státního či obchodního tajemství

Publication form

electronic version available online

RIV identification code

RIV/00216224:14330/15:00083221

Organization unit

Faculty of Informatics

ISSN

UT WoS

000361966300003

Keywords in English

Biological models; model annotation; systems biology; simulation; database

Tags

International impact, Reviewed
Změněno: 6/5/2016 03:32, RNDr. Pavel Šmerk, Ph.D.

Abstract

V originále

Traditional mathematical models of photosynthesis are based on mass action kinetics of light reactions. This approach requires the modeller to enumerate all the possible state combinations of the modelled chemical species. This leads to combinatorial explosion in the number of reactions although the structure of the model could be expressed more compactly. We explore the use of rule-based modelling, in particular, a simplified variant of Kappa, to compactly capture and automatically reduce existing mathematical models of photosynthesis. Finally, the reduction procedure is implemented in BioNetGen language and demonstrated on several ODE models of photosynthesis processes.

Links

EE2.3.20.0256, research and development project
Name: Vytvoření výzkumného týmu a mezinárodního konzorcia pro počítačový model buňky sinice