Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy
Compared To White Light Bronchoscopy in the Diagnostics of Lung
Tumours

J 2015

Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy Compared To White Light Bronchoscopy in the Diagnostics of Lung Tumours

ONDREJKA, Gustav, Ondřej MÁJEK, Jana SKŘIČKOVÁ and Richard TYL

Basic information

Original name

Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy Compared To White Light Bronchoscopy in the Diagnostics of Lung Tumours

Authors

ONDREJKA, Gustav (203 Czech Republic), Ondřej MÁJEK (203 Czech Republic), Jana SKŘIČKOVÁ (203 Czech Republic, guarantor, belonging to the institution) and Richard TYL (203 Czech Republic)

Edition

International Journal of Health Sciences and Research, New Delhi, International journal of health sciences and research, 2015, 2249-9571

Other information

Language

English

Type of outcome

Článek v odborném periodiku

Field of Study

30203 Respiratory systems

Country of publisher

India

Confidentiality degree

není předmětem státního či obchodního tajemství

RIV identification code

RIV/00216224:14110/15:00083334

Organization unit

Faculty of Medicine

Keywords in English

Lung cancer; Bronchoscopy; Narrow band imaging

Abstract

V originále

Background: Bronchoscopy plays an important role in the diagnostics of lung tumours. One of the technologies looking for their way in the diagnostics of pulmonary diseases is narrow band imaging. The aim of this study was to compare accuracy of examinations in the NBI and the white light (WL) modes in relation to biopsy results for the diagnoses of malignant tumour or severe dysplasia. Methods and results: A group of 500 patients have undergone a bronchoscopic examination in the NBI mode and afterwards in the white light. Biopsies were taken from all areas with pathological findings in both the modes for histological examination. Pathological bronchoscopic images were detected in a total of 382 patients. Positive findings in both the NBI mode and the WL mode were detected in 331 patients (66.2%). Discordant NBI-/WL+ findings were detected in 29 cases (5.8%) and discordant NBI+/WL- findings were detected in 22 cases (4.4%). The relative sensitivity of NBI compared to WL is 1.06 (p < 0.01; NBI sensitivity is significantly higher). The relative rate of false positive results in NBI compared to WL is 0.91 (p = 0.01; the rate of false positive results is significantly lower in NBI). Conclusions: The performed statistical evaluation shows a statistically significant increase in examination accuracy in NBI compared to WL. An NBI examination is able to differentiate between the necrotic avascular region of the tumour and the viable tissue very well even if an examination in the WL mode is not so explicit in this respect.

Citovat

ONDREJKA, Gustav, Ondřej MÁJEK, Jana SKŘIČKOVÁ and Richard TYL. Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy Compared To White Light Bronchoscopy in the Diagnostics of Lung Tumours. International Journal of Health Sciences and Research. New Delhi: International journal of health sciences and research, 2015, vol. 5, No 6, p. 80-88. ISSN 2249-9571.

@article{1305842,
   author = {Ondrejka, Gustav and Májek, Ondřej and Skřičková, Jana and Tyl, Richard},
   article_location = {New Delhi},
   article_number = {6},
   keywords = {Lung cancer; Bronchoscopy; Narrow band imaging},
   language = {eng},
   issn = {2249-9571},
   journal = {International Journal of Health Sciences and Research},
   title = {Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy Compared To White Light Bronchoscopy in the Diagnostics of Lung Tumours},
   volume = {5},
   year = {2015}
}

TY  - JOUR
ID  - 1305842
AU  - Ondrejka, Gustav - Májek, Ondřej - Skřičková, Jana - Tyl, Richard
PY  - 2015
TI  - Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy Compared To White Light Bronchoscopy in the Diagnostics of Lung Tumours
JF  - International Journal of Health Sciences and Research
VL  - 5
IS  - 6
SP  - 80-88
EP  - 80-88
PB  - International journal of health sciences and research
SN  - 22499571
KW  - Lung cancer
KW  - Bronchoscopy
KW  - Narrow band imaging
N2  - Background: Bronchoscopy plays an important role in the diagnostics of lung tumours. One of the technologies looking for their way in the diagnostics of pulmonary diseases is narrow band imaging. The aim of this study was to compare accuracy of examinations in the NBI and the white light (WL) modes in relation to biopsy results for the diagnoses of malignant tumour or severe dysplasia. Methods and results: A group of 500 patients have undergone a bronchoscopic examination in the NBI mode and afterwards in the white light. Biopsies were taken from all areas with pathological findings in both the modes for histological examination. Pathological bronchoscopic images were detected in a total of 382 patients. Positive findings in both the NBI mode and the WL mode were detected in 331 patients (66.2%). Discordant NBI-/WL+ findings were detected in 29 cases (5.8%) and discordant NBI+/WL- findings were detected in 22 cases (4.4%). The relative sensitivity of NBI compared to WL is 1.06 (p < 0.01; NBI sensitivity is significantly higher). The relative rate of false positive results in NBI compared to WL is 0.91 (p = 0.01; the rate of false positive results is significantly lower in NBI). Conclusions: The performed statistical evaluation shows a statistically significant increase in examination accuracy in NBI compared to WL. An NBI examination is able to differentiate between the necrotic avascular region of the tumour and the viable tissue very well even if an examination in the WL mode is not so explicit in this respect.
ER  -

ONDREJKA, Gustav, Ondřej MÁJEK, Jana SKŘIČKOVÁ and Richard TYL. Accuracy Analysis of Narrow Band Imaging (NBI) Bronchoscopy Compared To White Light Bronchoscopy in the Diagnostics of Lung Tumours. \textit{International Journal of Health Sciences and Research}. New Delhi: International journal of health sciences and research, 2015, vol.~5, No~6, p.~80-88. ISSN~2249-9571.

Detailed Information on Publication Record