RYZÍ, Michal, Milan BRÁZDIL, Zdeněk NOVÁK, Jan HEMZA, Jan CHRASTINA, Hana OŠLEJŠKOVÁ, Ivan REKTOR a Robert KUBA. Long-term outcomes in patients after epilepsy surgery failure. Epilepsy Research. Amsterdam: Elsevier Science, 2015, roč. 110, February, s. 71-77. ISSN 0920-1211. doi:10.1016/j.eplepsyres.2014.11.011.
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Základní údaje
Originální název Long-term outcomes in patients after epilepsy surgery failure
Autoři RYZÍ, Michal (203 Česká republika, garant, domácí), Milan BRÁZDIL (203 Česká republika, domácí), Zdeněk NOVÁK (203 Česká republika), Jan HEMZA (203 Česká republika), Jan CHRASTINA (203 Česká republika, domácí), Hana OŠLEJŠKOVÁ (203 Česká republika, domácí), Ivan REKTOR (203 Česká republika, domácí) a Robert KUBA (203 Česká republika, domácí).
Vydání Epilepsy Research, Amsterdam, Elsevier Science, 2015, 0920-1211.
Další údaje
Originální jazyk angličtina
Typ výsledku Článek v odborném periodiku
Obor 30000 3. Medical and Health Sciences
Stát vydavatele Nizozemsko
Utajení není předmětem státního či obchodního tajemství
Impakt faktor Impact factor: 2.237
Kód RIV RIV/00216224:14110/15:00083356
Organizační jednotka Lékařská fakulta
Doi http://dx.doi.org/10.1016/j.eplepsyres.2014.11.011
UT WoS 000349592800010
Klíčová slova anglicky Epilepsy surgery; Failure; Reoperation; Vagus nerve stimulation; Treatment options
Štítky EL OK, podil
Příznaky Mezinárodní význam, Recenzováno
Změnil Změnila: Ing. Mgr. Věra Pospíšilíková, učo 9005. Změněno: 16. 7. 2015 09:36.
Anotace
Purpose: The primary aim of this study was to analyze the long-term outcomes of patients who were classified as Engel IV one year after resective epilepsy surgery. The secondary objectives were to evaluate the effectiveness of different treatment options and to examine the reasons that the patients did not undergo resective reoperation. Methods: Our study was designed as a retrospective open-label investigation of the long-term outcomes of 34 patients (12% of all surgically treated patients) who were classified as Engel IV one year after epilepsy surgery. Results: At the last follow-up visit (average of 7.6 +/- 4.2 years after surgery), 12 of the 34 examined patients (35.3%) were still classified as Engel IV; 22 of the 34 patients (64.7%) were improved (Engel I III). Of the 34 patients, 8 (23.5%) achieved an excellent outcome, classified as Engel I, 3 patients (8.8%) were classified as Engel II, and 11 patients (32.4%) as Engel III. The seizure outcome in the patients classified as Engel I was achieved by resective reoperation in 4; by a change in antiepileptic medication in 3 patients; and by vagus nerve stimulation (VHS) in 1 patient. The seizure outcome of Engel II was achieved by a change in antiepileptic medication in all 3 patients. Of the 34 patients, a total of 6 (17.6%) underwent resective reoperation only. The major reasons for this were the absence of a plausible hypothesis for invasive re-evaluation, the risk of postoperative deficit, and multifocal epilepsy in the rest of patients. Conclusion: Although the reoperation rate was relatively low in our series, we can achieve better or even excellent seizure outcomes using other procedures in patients for whom resective surgery initially failed.
Návaznosti
ED1.1.00/02.0068, projekt VaVNázev: CEITEC - central european institute of technology
VytisknoutZobrazeno: 25. 6. 2022 19:54