STOICA, Adrian, Anton MANAKHOV, Josef POLČÁK, Pavel ONDRAČKA, Vilma BURŠÍKOVÁ, Renata ZAJÍČKOVÁ, Jiřina MEDALOVÁ and Lenka ZAJÍČKOVÁ. Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition. Biointerphases. Melville (USA): American Institute of Physics, 2015, vol. 10, No 2, p. nestránkováno, 9 pp. ISSN 1934-8630. doi:10.1116/1.4920978.
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Basic information
Original name Cell proliferation on modified DLC thin films prepared by plasma enhanced chemical vapor deposition
Authors STOICA, Adrian (642 Romania, belonging to the institution), Anton MANAKHOV (643 Russian Federation, belonging to the institution), Josef POLČÁK (203 Czech Republic), Pavel ONDRAČKA (203 Czech Republic, belonging to the institution), Vilma BURŠÍKOVÁ (203 Czech Republic, belonging to the institution), Renata ZAJÍČKOVÁ (203 Czech Republic, guarantor, belonging to the institution), Jiřina MEDALOVÁ (203 Czech Republic, belonging to the institution) and Lenka ZAJÍČKOVÁ (203 Czech Republic, belonging to the institution).
Edition Biointerphases, Melville (USA), American Institute of Physics, 2015, 1934-8630.
Other information
Original language English
Type of outcome Article in a journal
Field of Study 10305 Fluids and plasma physics
Country of publisher United States of America
Confidentiality degree is not subject to a state or trade secret
Impact factor Impact factor: 2.105
RIV identification code RIV/00216224:14740/15:00083399
Organization unit Central European Institute of Technology
UT WoS 000357195600038
Keywords in English DLC thin films; Cell proliferation; plasma
Tags podil, rivok
Tags International impact, Reviewed
Changed by Changed by: Mgr. Jiřina Medalová, Ph.D., učo 176525. Changed: 13. 3. 2018 10:59.
Recently, diamondlike carbon (DLC) thin films have gained interest for biological applications, such as hip and dental prostheses or heart valves and coronary stents, thanks to their high strength and stability. However, the biocompatibility of the DLC is still questionable due to its low wettability and possible mechanical failure (delamination). In this work, DLC:N:O and DLC: SiOx thin films were comparatively investigated with respect to cell proliferation. Thin DLC films with an addition of N, O, and Si were prepared by plasma enhanced CVD from mixtures of methane, hydrogen, and hexamethyldisiloxane. The films were optically characterized by infrared spectroscopy and ellipsometry in UV-visible spectrum. The thickness and the optical properties were obtained from the ellipsometric measurements. Atomic composition of the films was determined by Rutherford backscattering spectroscopy combined with elastic recoil detection analysis and by x-ray photoelectron spectroscopy. The mechanical properties of the films were studied by depth sensing indentation technique. The number of cells that proliferate on the surface of the prepared DLC films and on control culture dishes were compared and correlated with the properties of as-deposited and aged films. The authors found that the level of cell proliferation on the coated dishes was high, comparable to the untreated (control) samples. The prepared DLC films were stable and no decrease of the biocompatibility was observed for the samples aged at ambient conditions.
ED1.1.00/02.0068, research and development projectName: CEITEC - central european institute of technology
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