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@proceedings{1308695,
author = {Valová, Simona and Bořilová Linhartová, Petra and Kaňková, Kateřina and Poskerová, Hana and Vokurka, Jan and Fassmann, Antonín and Izakovičová Hollá, Lydie},
booktitle = {The 12th World Congress on Inflammation},
doi = {http://dx.doi.org/10.1007/s00011-015-0839-4},
keywords = {IL-6; polymorphism; chronic periodontitis; diabetes mellitus; haplotype},
language = {eng},
title = {Haplotype analysis of interleukin-6 gene promoter polymorphisms in patients with chronic periodontitis and diabetes mellitus},
year = {2015}
}
TY - CONF
ID - 1308695
AU - Valová, Simona - Bořilová Linhartová, Petra - Kaňková, Kateřina - Poskerová, Hana - Vokurka, Jan - Fassmann, Antonín - Izakovičová Hollá, Lydie
PY - 2015
TI - Haplotype analysis of interleukin-6 gene promoter polymorphisms in patients with chronic periodontitis and diabetes mellitus
KW - IL-6
KW - polymorphism
KW - chronic periodontitis
KW - diabetes mellitus
KW - haplotype
N2 - The aim of our study was to investigate the association of single nucleotide polymorphisms at positions -174G/C (rs1800795), -572G/C (rs1800796) and -597G/A (rs1800797), and their combinations (haplotypes) in patients with CP, type 1 DM (T1DM) and type 2 DM (T2DM) in comparison with healthy controls. Our results indicate that different IL-6 promoter haplotypes can affect the risk for CP and DM development. However, the individual IL-6 gene promoter polymorphisms do not act independently and may affect each other.
ER -
VALOVÁ, Simona, Petra BOŘILOVÁ LINHARTOVÁ, Kateřina KAŇKOVÁ, Hana POSKEROVÁ, Jan VOKURKA, Antonín FASSMANN a Lydie IZAKOVIČOVÁ HOLLÁ. Haplotype analysis of interleukin-6 gene promoter polymorphisms in patients with chronic periodontitis and diabetes mellitus. In \textit{The 12th World Congress on Inflammation}. ISSN~1023-3830. doi:10.1007/s00011-015-0839-4. 2015.
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