| KAZDA, Tomáš, Petr POSPÍŠIL, M. VRZAL, O. SEVELA, T. PROCHAZKA, Radim JANČÁLEK, Pavel ŠLAMPA and N.N. LAACK. Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report. CANCER RADIOTHERAPIE. BRIDGEWATER: ELSEVIER, 2015, vol. 19, No 3, p. 187-191. ISSN 1278-3218. Available from: https://dx.doi.org/10.1016/j.canrad.2014.11.013. |
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@article{1309114,
author = {Kazda, Tomáš and Pospíšil, Petr and Vrzal, M. and Sevela, O. and Prochazka, T. and Jančálek, Radim and Šlampa, Pavel and Laack, N.N.},
article_location = {BRIDGEWATER},
article_number = {3},
doi = {http://dx.doi.org/10.1016/j.canrad.2014.11.013},
keywords = {Hippocampus; Astrocytoma; Neurocognition; Cranial irradiation},
language = {eng},
issn = {1278-3218},
journal = {CANCER RADIOTHERAPIE},
title = {Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report},
volume = {19},
year = {2015}
}
TY - JOUR
ID - 1309114
AU - Kazda, Tomáš - Pospíšil, Petr - Vrzal, M. - Sevela, O. - Prochazka, T. - Jančálek, Radim - Šlampa, Pavel - Laack, N.N.
PY - 2015
TI - Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report
JF - CANCER RADIOTHERAPIE
VL - 19
IS - 3
SP - 187-191
EP - 187-191
PB - ELSEVIER
SN - 12783218
KW - Hippocampus
KW - Astrocytoma
KW - Neurocognition
KW - Cranial irradiation
N2 - Timing of radiotherapy for low-grade gliomas is still controversial due to concerns of possible adverse late effects. Prevention of possible late cognitive sequelae by hippocampal avoidance has shown promise in phase II trials. A patient with progressive low-grade glioma with gradual dedifferentiation into anaplastic astrocytoma is presented along with description of radiotherapy planning process attempting to spare the hippocampus. To our knowledge, this is the first described case using volumetric modulated arc technique to spare hippocampus during transformed low-grade glioma radiotherapy. Using modern intensity-modulated radiotherapy systems it is possible to selectively spare hippocampus together with other standard organs at risk. For selected patients, an attempt to spare hippocampus can be considered as long as other dose characteristics are not significantly compromised compared to standard treatment plan created without any effort to avoid hippocampus.
ER -
KAZDA, Tomáš, Petr POSPÍŠIL, M. VRZAL, O. SEVELA, T. PROCHAZKA, Radim JANČÁLEK, Pavel ŠLAMPA and N.N. LAACK. Volumetric modulated arc therapy for hippocampal-sparing radiotherapy in transformed low-grade glioma: A treatment planning case report. \textit{CANCER RADIOTHERAPIE}. BRIDGEWATER: ELSEVIER, 2015, vol.~19, No~3, p.~187-191. ISSN~1278-3218. Available from: https://dx.doi.org/10.1016/j.canrad.2014.11.013.
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