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@article{1312214,
author = {Kejnovský, Eduard and Tokan, Viktor and Lexa, Matej},
article_number = {3},
doi = {http://dx.doi.org/10.1007/s10577-015-9491-7},
keywords = {transposable elements; LTR retrotransposons; DNA and RNA quadruplexes; G-quadruplexes; transcription; recombination; replication},
language = {eng},
issn = {0967-3849},
journal = {Chromosome Research},
title = {Transposable elements and G-quadruplexes},
url = {http://link.springer.com/article/10.1007/s10577-015-9491-7},
volume = {23},
year = {2015}
}
TY - JOUR
ID - 1312214
AU - Kejnovský, Eduard - Tokan, Viktor - Lexa, Matej
PY - 2015
TI - Transposable elements and G-quadruplexes
JF - Chromosome Research
VL - 23
IS - 3
SP - 615-623
EP - 615-623
PB - Springer Netherlands
SN - 09673849
KW - transposable elements
KW - LTR retrotransposons
KW - DNA and RNA quadruplexes
KW - G-quadruplexes
KW - transcription
KW - recombination
KW - replication
UR - http://link.springer.com/article/10.1007/s10577-015-9491-7
L2 - http://link.springer.com/article/10.1007/s10577-015-9491-7
N2 - A significant part of eukaryotic genomes is formed by transposable elements (TEs) containing not only genes but also regulatory sequences. Some of the regulatory sequences located within TEs can form secondary structures like hairpins or three-stranded (triplex DNA) and four-stranded (quadruplex DNA) conformations. This review focuses on recent evidence showing that G-quadruplex-forming sequences in particular are often present in specific parts of TEs in plants and humans. We discuss the potential role of these structures in the TE life cycle as well as the impact of G-quadruplexes on replication, transcription, translation, chromatin status, and recombination. The aim of this review is to emphasize that TEs may serve as vehicles for the genomic spread of G-quadruplexes. These non-canonical DNA structures and their conformational switches may constitute another regulatory system that, together with small and long non-coding RNA molecules and proteins, contribute to the complex cellular network resulting in the large diversity of eukaryotes.
ER -
KEJNOVSKÝ, Eduard, Viktor TOKAN and Matej LEXA. Transposable elements and G-quadruplexes. \textit{Chromosome Research}. Springer Netherlands, 2015, vol.~23, No~3, p.~615-623. ISSN~0967-3849. Available from: https://dx.doi.org/10.1007/s10577-015-9491-7.
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