BRIM, Luboš, Martin DEMKO, Samuel PASTVA and David ŠAFRÁNEK. High-Performance Discrete Bifurcation Analysis for Piecewise-Affine Dynamical Systems. In Alessandro Abate, David Šafránek. Hybrid Systems Biology Fourth International Workshop, HSB 2015, Madrid, Spain, September 4-5, 2015. Revised Selected Papers. LNCS 9271. Neuveden: Springer International Publishing, 2015, p. 58-74. ISBN 978-3-319-26915-3. Available from: https://dx.doi.org/10.1007/978-3-319-26916-0_4.
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Basic information
Original name High-Performance Discrete Bifurcation Analysis for Piecewise-Affine Dynamical Systems
Authors BRIM, Luboš (203 Czech Republic, belonging to the institution), Martin DEMKO (703 Slovakia, belonging to the institution), Samuel PASTVA (703 Slovakia, belonging to the institution) and David ŠAFRÁNEK (203 Czech Republic, guarantor, belonging to the institution).
Edition LNCS 9271. Neuveden, Hybrid Systems Biology Fourth International Workshop, HSB 2015, Madrid, Spain, September 4-5, 2015. Revised Selected Papers, p. 58-74, 17 pp. 2015.
Publisher Springer International Publishing
Other information
Original language English
Type of outcome Proceedings paper
Field of Study 10201 Computer sciences, information science, bioinformatics
Country of publisher Czech Republic
Confidentiality degree is not subject to a state or trade secret
Publication form printed version "print"
WWW elektronická verze v nakladatelství Springer
Impact factor Impact factor: 0.402 in 2005
RIV identification code RIV/00216224:14330/15:00081134
Organization unit Faculty of Informatics
ISBN 978-3-319-26915-3
ISSN 0302-9743
Doi http://dx.doi.org/10.1007/978-3-319-26916-0_4
Keywords in English bifurcation analysis; model checking; dynamical systems; formal methods
Tags International impact, Reviewed
Changed by Changed by: RNDr. Pavel Šmerk, Ph.D., učo 3880. Changed: 28/4/2016 21:13.
Abstract
Analysis of equilibria, their stability and instability, is an unavoidable ingredient of model analysis in systems biology. In particular, bifurcation analysis which focuses on behaviour of phase portraits under variations of parameters is of great importance. We propose a novel method for bifurcation analysis that employs coloured model checking to analyse phase portraits bifurcation in rectangular abstractions of piecewise-affine systems. The algorithm works on clusters of workstations and multi-core computers to allow scalability. We demonstrate the method on a repressilator genetic regulatory network.
Links
GA15-11089S, research and development projectName: Získávání parametrů biologických modelů pomocí techniky ověřování modelů
Investor: Czech Science Foundation
MUNI/A/1159/2014, interní kód MUName: Rozsáhlé výpočetní systémy: modely, aplikace a verifikace IV.
Investor: Masaryk University, Category A
MUNI/A/1206/2014, interní kód MUName: Zapojení studentů Fakulty informatiky do mezinárodní vědecké komunity (Acronym: SKOMU)
Investor: Masaryk University, Category A
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