Detailed Information on Publication Record
2015
Insect immunity after invasion of entomopathogenic nematodes
HYRŠL, Pavel, Pavel DOBEŠ, Badrul AREFIN, Jakub BERKA, Lucie KUČEROVÁ et. al.Basic information
Original name
Insect immunity after invasion of entomopathogenic nematodes
Name in Czech
Insect immunity after invasion of entomopathogenic nematodes
Authors
HYRŠL, Pavel (203 Czech Republic, guarantor, belonging to the institution), Pavel DOBEŠ (203 Czech Republic, belonging to the institution), Badrul AREFIN (752 Sweden), Jakub BERKA (203 Czech Republic, belonging to the institution), Lucie KUČEROVÁ (752 Sweden), Robert MARKUS (752 Sweden), Zhi WANG (752 Sweden), Michal ŽUROVEC (203 Czech Republic) and Ulrich THEOPOLD (752 Sweden)
Edition
Workshop: At the crossroads between insect immunology, physiology and ecology, 2015
Other information
Language
English
Type of outcome
Konferenční abstrakt
Field of Study
30102 Immunology
Country of publisher
Czech Republic
Confidentiality degree
není předmětem státního či obchodního tajemství
RIV identification code
RIV/00216224:14310/15:00080483
Organization unit
Faculty of Science
Keywords (in Czech)
imunita; Drosophila; hmyz
Keywords in English
immunity; Drosophila; insect
Změněno: 19/10/2015 18:32, doc. RNDr. Pavel Hyršl, Ph.D.
V originále
Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection. Our research is supported by research grants from the Swedish Foundation for International Cooperation in Research and Higher Education (STINT) and by grant from Ministry of Agriculture of Czech Republic (NAZV-KUS QJ1210047).
In Czech
Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection. Our research is supported by research grants from the Swedish Foundation for International Cooperation in Research and Higher Education (STINT) and by grant from Ministry of Agriculture of Czech Republic (NAZV-KUS QJ1210047).
Links
| QJ1210047, research and development project |
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