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@proceedings{1314402, author = {Hyršl, Pavel and Dobeš, Pavel and Arefin, Badrul and Berka, Jakub and Kučerová, Lucie and Markus, Robert and Wang, Zhi and Žurovec, Michal and Theopold, Ulrich}, booktitle = {Workshop: At the crossroads between insect immunology, physiology and ecology}, keywords = {immunity; Drosophila; insect}, language = {eng}, title = {Insect immunity after invasion of entomopathogenic nematodes}, year = {2015} }
TY - CONF ID - 1314402 AU - Hyršl, Pavel - Dobeš, Pavel - Arefin, Badrul - Berka, Jakub - Kučerová, Lucie - Markus, Robert - Wang, Zhi - Žurovec, Michal - Theopold, Ulrich PY - 2015 TI - Insect immunity after invasion of entomopathogenic nematodes KW - immunity KW - Drosophila KW - insect N2 - Entomopathogenic nematodes and their associated bacteria comprise together highly pathogenic complex able to invade and kill insect host within two days. Both bacteria and nematodes produce variety of factors interacting with insect immune system that help to overcome host defences. The tripartite model (Drosophila, nematodes, bacteria) was established and used to show an immune function for candidate genes using different Drosophila mutants or RNAi lines with defects in clotting or other branches of the immune system. We demonstrated an immune function during nematode infection for known clotting enzymes and substrates, recognition molecules, eicosanoids etc. In conclusion, we show that the Heterorhabditis/Photorhabdus infection model is suitable to identify novel regulators of innate immunity and we bring evidence of coagulation immune function in insects against nematode infection. Our research is supported by research grants from the Swedish Foundation for International Cooperation in Research and Higher Education (STINT) and by grant from Ministry of Agriculture of Czech Republic (NAZV-KUS QJ1210047). ER -
HYRŠL, Pavel, Pavel DOBEŠ, Badrul AREFIN, Jakub BERKA, Lucie KUČEROVÁ, Robert MARKUS, Zhi WANG, Michal ŽUROVEC and Ulrich THEOPOLD. Insect immunity after invasion of entomopathogenic nematodes. In \textit{Workshop: At the crossroads between insect immunology, physiology and ecology}. 2015.
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