ANDRAŠINA, Tomáš, Sung Kwon KANG, Jong Ho MOON, Tomáš GROLICH a Michal CRHA. Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region. In 9th Meeting of the Society of Gastrointestinal Intervention. 2015.
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Základní údaje
Originální název Partially covered, self-expandable metal stents with anti-reflux valves for malignancies comprising hilar region
Autoři ANDRAŠINA, Tomáš (703 Slovensko, garant, domácí), Sung Kwon KANG (410 Korejská republika), Jong Ho MOON (410 Korejská republika), Tomáš GROLICH (203 Česká republika, domácí) a Michal CRHA (203 Česká republika).
Vydání 9th Meeting of the Society of Gastrointestinal Intervention, 2015.
Další údaje
Originální jazyk angličtina
Typ výsledku Konferenční abstrakt
Obor 30000 3. Medical and Health Sciences
Stát vydavatele Korejská republika
Utajení není předmětem státního či obchodního tajemství
Kód RIV RIV/00216224:14110/15:00084697
Organizační jednotka Lékařská fakulta
Klíčová slova anglicky self expandable metal; stent; biliary antireflux valve
Štítky EL OK
Změnil Změnila: Ing. Mgr. Věra Pospíšilíková, učo 9005. Změněno: 5. 12. 2016 13:29.
Anotace
Objective: To prove feasibility of percutaneous parallel implantation of partially covered, self-expandable metal stents (PC-SEMS) with antireflux valves (AR valves) in in-vivo model. Method: The novel design of PC-SEMS suitable for patients with hilar malignancies was developed. For percutaneous implantation of stent with AR valve, specific type of introducer is needed to prevent closing and crumpling of valve during implantation procedure. Stent is half covered with e-PTFE membrane, also forming AR valve. Proximal half of the stent is bare to allow flow of bile from segmental branches of biliary tree arising in hilar region. In-vivo experiment was chosen to test safe deployment of two PC-SEMS with AR valve. Parallel and synchronous implantation of stents was used in cross-bred piglet model. The procedure was performed under general anaesthesia with simulation of percutaneous approach. Open laparotomic view of duodenum was used for observation of AR valve. One week later the experimental model was euthanized and autopsy was performed to assess stent patency, presence of intraluminal content and function of AR valve. Results: The implantation of SEMS with AR valve is performed with an extra step. By retrieving of stent introducer sheath, a metal bumper which maintains the open position of antireflux valve is opened. The extra step of recapturing metal bumper is needed to safely remove the introducer system. For the synchronous and parallel implantation of two stents whole process of implantation was completed without collision or affecting the AR valve system. The extra step prolonged the procedure insignificantly (8 and 9 seconds). The autopsy of model proved full patency of SEMS and AR valve. No intraluminal content was found inside the stents. Conclusion: The new self expandable partially covered stent with antireflux valve is suitable for parallel and synchronous percutaneous implantation. No significant reflux was observed during experimental period.
Návaznosti
ROZV/20/LF/2015, interní kód MUNázev: LF - Příspěvek IP 2015
Investor: Ministerstvo školství, mládeže a tělovýchovy ČR, LF - Příspěvek IP 2015
VytisknoutZobrazeno: 19. 4. 2024 07:17